⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772348 | 0.76 | PRKCI (0.45) | — | |
| SCHEMBL12125050 | 0.75 | KDM4E (0.43) | — | |
| SCHEMBL9545148 | 0.72 | POLB (0.48) | — | |
| SCHEMBL4883169 | 0.71 | TSHR (0.50) | — | |
| SCHEMBL16189392 | 0.71 | — | — | |
| SCHEMBL13633835 | 0.70 | CHRM2 (0.37) | — | |
| SCHEMBL3141353 | 0.69 | TLR8 (0.46) | — | |
| SCHEMBL23192557 | 0.69 | ALDH1A1 (0.49) | — | |
| SCHEMBL23751998 | 0.68 | TLR8 (0.45) | — | |
| SCHEMBL20139100 | 0.68 | TLR8 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037742-B2 | Process for coating fibers containing polar moieties | POLITECNICO DI MILANO (IT) | 2024-07-16 | — | — | US | disclosed |
| US-20220081413-A1 | SYNTHESIS OF QUINAZOLINE COMPOUNDS | GENENTECH, INC. (US) | 2022-03-17 | — | — | US | disclosed |
| US-9872846-B2 | High penetration compositions and uses thereof | TECHFIELDS PHARMA CO., LTD. (CN) | 2018-01-23 | — | — | US | disclosed |
| US-20170209585-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO LTD (CN) | 2017-07-27 | — | — | US | disclosed |
| US-20170209404-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | PREMIER RESEARCH INTERNATIONAL, LLC | 2017-07-27 | — | — | US | disclosed |
| US-20120302710-A1 | COMPLEXES FOR USE IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-11-29 | — | — | US | disclosed |
| US-8183351-B2 | Avermectin derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-22 | — | — | US | disclosed |
| US-8183351-B2 | Avermectin derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-22 | — | — | US | disclosed |
| US-20110150834-A1 | CRTH2 MODULATORS | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2011-06-23 | — | — | US | disclosed |
| US-20100234312-A1 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100210618-A1 | PIPERIDINE/PIPERAZINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-08-19 | — | — | US | disclosed |
| US-7648738-B2 | for photopolymerization; photography, relief imaging; color filters | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-19 | — | — | US | disclosed |
| US-7648738-B2 | for photopolymerization; photography, relief imaging; color filters | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-19 | — | — | US | disclosed |
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | disclosed |
| US-20090232867-A1 | Modified conductive surfaces having active substances attached thereto | ELUTEX LTD. (IL) | 2009-09-17 | — | — | US | disclosed |
| US-20090123514-A1 | Electropolymerizable Monomers and Polymeric Coatings on Implantable Devices Prepared Therefrom | ELUTEX LTD. (IL) | 2009-05-14 | — | — | US | disclosed |
| US-7498341-B2 | antidiabetic agents; type 2 diabetes | SANOFI AVENTIS DEUTSCHLAND GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1567518-B1 | OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008019784-A2 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
| EP-0287988-A2 | Pyrrole aldehydes, their preparation and use | CASSELLA Aktiengesellschaft (DE) | 1988-10-26 | — | — | EP | disclosed |