SCHEMBL23751998

SCHEMBL23751998

CCCCCCCCCCCCCCCCCCn1c(C)ccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 5/20 0.45
PRKCI P41743 1/20 0.44
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
HTT P42858 4/20 0.44
GALR3 O60755 2/20 0.44
POLB P06746 2/20 0.44
ATM Q13315 2/20 0.44
MAPK1 P28482 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HSP90AA1 P07900 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
RAD52 P43351 1/20 0.44
PAX8 Q06710 1/20 0.44
NR2F2 P24468 1/20 0.44
APOBEC3A P31941 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20139100 1.00 TLR8 (0.45) TLR8PRKCINPC1RAB9AHTT
SCHEMBL14958647 1.00 TLR8 (0.45) TLR8PRKCINPC1RAB9AHTT
SCHEMBL14958645 1.00 TLR8 (0.45) TLR8PRKCINPC1RAB9AHTT
SCHEMBL3141353 0.98 TLR8 (0.46) TLR8PRKCINPC1RAB9AHTT
SCHEMBL4883169 0.90 TSHR (0.50) TLR8PRKCIPOLBNPSR1LMNA
SCHEMBL11339139 0.90 PRKCI (0.50) TLR8PRKCIPOLBNPSR1LMNA
SCHEMBL31469892 0.88 MGLL (0.53) TLR8LMNAKDM4EPTGS1MGLL
SCHEMBL14243368 0.86 TLR8 (0.46) TLR8NPC1RAB9AHTTGALR3
SCHEMBL16405004 0.84 GPR84 (0.39) TLR8NPC1RAB9AHTTGALR3
SCHEMBL7215402 0.81 TLR8 (0.40) TLR8PRKCINPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790849-B1 CEMENT-BASED COMPOSITE MATERIALS COMPRISING SP2 HYBRIDIZED CARBON ALLOTROPES MILANO POLITECNICO (IT) 2025-11-26 EP disclosed
WO-2025027538-A1 PROCESS FOR PREPARING STABLE AND HOMOGENEOUS DISPERSIONS OF SP2 CARBON ALLOTROPES IN LIPOPHILIC MATRIXES AND RELATED COMPOSITE MATERIALS OBTAINABLE THEREFROM ENI S.P.A. (IT) 2025-02-06 WO disclosed
US-12037742-B2 Process for coating fibers containing polar moieties POLITECNICO DI MILANO (IT) 2024-07-16 US disclosed
CN-112204081-B Method for coating fibres containing polar moieties 米兰综合工科大学 2023-06-27 CN disclosed
EP-3790926-B1 PROCESS FOR COATING FIBERS CONTAINING POLAR MOIETIES MILANO POLITECNICO (IT) 2022-06-29 EP disclosed
US-20210254275-A1 PROCESS FOR COATING FIBERS CONTAINING POLAR MOIETIES POLITECNICO DI MILANO (IT) 2021-08-19 US disclosed
CN-112204081-A Method for coating fibers containing polar moieties 米兰综合工科大学 2021-01-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037742-B2 Process for coating fibers containing polar moieties PCBP1, CAPG, CKAP4 TLR8 3020/4885PRKCI 3830/4885NPC1 4052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.