SCHEMBL4883169

SCHEMBL4883169

CCCCn1c(C)ccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ALDH1A1 P00352 4/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PRKCI P41743 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PGR P06401 2/20 0.41
RORA P35398 2/20 0.41
RORC P51449 2/20 0.41
RORB Q92753 2/20 0.41
RGS4 P49798 2/20 0.41
RGS8 P57771 1/20 0.41
TLR8 Q9NR97 2/20 0.40
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3141353 0.92 TLR8 (0.46) TSHRALDH1A1KMT2AKDM4EMEN1
SCHEMBL20139100 0.90 TLR8 (0.45) TSHRALDH1A1KDM4ESMN1; SMN2PRKCI
SCHEMBL14958647 0.90 TLR8 (0.45) TSHRALDH1A1KDM4ESMN1; SMN2PRKCI
SCHEMBL23751998 0.90 TLR8 (0.45) TSHRALDH1A1KDM4ESMN1; SMN2PRKCI
SCHEMBL14958645 0.90 TLR8 (0.45) TSHRALDH1A1KDM4ESMN1; SMN2PRKCI
SCHEMBL11489950 0.83 ALDH1A1 (0.43) TSHRALDH1A1KMT2AKDM4EMEN1
SCHEMBL11339139 0.83 PRKCI (0.50) TSHRALDH1A1KMT2AKDM4EMEN1
SCHEMBL9772348 0.80 PRKCI (0.45) ALDH1A1KMT2AKDM4EMEN1GAA
SCHEMBL31469892 0.80 MGLL (0.53) TSHRALDH1A1KDM4ETDP1TLR8
SCHEMBL3355831 0.78 KDM4E (0.42) TSHRALDH1A1KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105381-A Preparation method of biomass-based 2, 5-dimethyl-N-substituted pyrrole derivative 贵州大学 2021-07-13 CN claimed
CN-113105381-A Preparation method of biomass-based 2, 5-dimethyl-N-substituted pyrrole derivative 贵州大学 2021-07-13 CN disclosed
US-20200165163-A1 TRANSPARENT HEAT-SHIELDING/HEAT-INSULATING MEMBER, AND METHOD FOR MANUFACTURING SAME MAXELL HOLDINGS, LTD. (JP) 2020-05-28 US disclosed
US-9759844-B2 Film mirror, film mirror manufacturing method, film mirror for photovoltaic power generation, and reflection device for photovoltaic power generation Konica Minolta, Inc. (JP) 2017-09-12 US disclosed
US-9494338-B2 Solar light collecting mirror and solar thermal power generation system having solar light collecting mirror Konica Minolta, Inc. (JP) 2016-11-15 US disclosed
EP-2518536-B1 FILM MIRROR, PROCESS FOR PRODUCTION OF SAME, AND REFLECTION DEVICE FOR SOLAR POWER GENERATION PURPOSES COMPRISING SAME KONICA MINOLTA ADVANCED LAYERS (JP) 2016-05-04 EP disclosed
US-9316415-B2 Film mirror, production process of same and reflection device for solar power generation comprising same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2016-04-19 US disclosed
EP-2960688-A1 SUNLIGHT-COLLECTING FILM MIRROR AND METHOD FOR PRODUCING SAME Fujifilm Corporation (JP) 2015-12-30 EP disclosed
US-20150369974-A1 FILM MIRROR FOR SOLAR RADIATION COLLECTION AND METHOD FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed
US-9110228-B2 Film mirror, film mirror for solar power generation and reflection device for solar power generation KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-08-18 US disclosed
US-20120257273-A1 FILM MIRROR, AND METHOD OF MANUFACTURING THE SAME AND REFLECTION DEVICE FOR SOLAR HEAT POWER GENERATION KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2012-10-11 US disclosed
US-20120257295-A1 FILM MIRROR, AND METHOD OF MANUFACTURING THE SAME AND REFLECTION DEVICE FOR SOLAR HEAT POWER GENERATION KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2012-10-11 US disclosed
US-20120257274-A1 FILM MIRROR, PRODUCTION PROCESS OF SAME AND REFLECTION DEVICE FOR SOLAR POWER GENERATION COMPRISING SAME KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2012-10-11 US disclosed
EP-2189464-A1 Terminating compounds, polymers, and their uses in rubber compositions and tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 2010-05-26 EP disclosed
US-20080281105-A1 Novel Quinolinium Salts and Derivatives IMMUSOL INCORPORATED (US) 2008-11-13 US disclosed
EP-1841428-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES Immusol Incorporated (US) 2007-10-10 EP disclosed
WO-2006078754-A1 NOVEL QUINOLINIUM SALTS AND DERIVATIVES IMMUSOL INCORPORATED (US) 2006-07-27 WO disclosed
US-6254980-B1 COLLOID OR MICELLE OF A SLIGHTLY WATER SOLUBLE ORGANIC CORROSION INHIBITOR AS AN ORGANIC LAYER MIXED WITH AND DISPERSED IN A MATRIX RESIN; WITHOUT USING ANY HEXAVALENT CHROMIUM NIPPON STEEL CORPORATION (JP) 2001-07-03 US disclosed
EP-0870549-B1 METALLIC SHEET HAVING RUST-PREVENTIVE ORGANIC COATING THEREON, PROCESS FOR THE PRODUCTION THEREOF AND TREATING FLUID THEREFOR NIPPON STEEL CORP (JP) 2001-03-21 EP disclosed
EP-0870549-A1 METALLIC SHEET HAVING RUST-PREVENTIVE ORGANIC COATING THEREON, PROCESS FOR THE PRODUCTION THEREOF AND TREATING FLUID THEREFOR NIPPON STEEL CORPORATION (JP) 1998-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281105-A1 Novel Quinolinium Salts and Derivatives NQO2, MCL1, KRAS TSHR 3448/4885ALDH1A1 3206/4885KMT2A 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.