SCHEMBL6760799

SCHEMBL6760799

[CH2]Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PREP P48147 4/20 0.45
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
CA9 Q16790 4/20 0.41
DRD2 P14416 1/20 0.33
CASP3 P42574 1/20 0.31
CASP7 P55210 1/20 0.31
ELANE P08246 1/20 0.31
IDO1 P14902 1/20 0.31
AGXT P21549 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6763899 0.83 PREP (0.53) PREPCA12CA1CA9
SCHEMBL12426281 0.82 PREP (0.46) PREPCA12CA1CA9
SCHEMBL1601708 0.82 PREP (0.46) PREPCA12CA1CA9DRD2
SCHEMBL4785220 0.82 PREP (0.50) PREPCA12CA1CA9
SCHEMBL2087006 0.81 PREP (0.45) PREPCA12CA1CA9DRD2
SCHEMBL318210 0.81 PPARA (0.47) PREPCA12CA1CA9DRD2
SCHEMBL4676713 0.81 IDO1 (0.50) PREPCA12CA1CA9DRD2
SCHEMBL14384880 0.81 PREP (0.45) PREPCA12CA1CA9DRD2
SCHEMBL11957424 0.81 PREP (0.45) PREPCA12CA1CA9
SCHEMBL31643222 0.81 PREP (0.49) PREPCA12CA1CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 PREP 4570/4885CA12 3922/4885CA1 1373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.