Sugi Predict

Sugi Predict / Compounds / SCHEMBL318210

SCHEMBL318210

SCHEMBL318210

CC(C)(C)[Si](C)(C)Oc1ccc(CO)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 3/20 0.47
▸ PPARG P37231 1/20 0.47
▸ PREP P48147 4/20 0.45
▸ LTA4H P09960 1/20 0.42
▸ CA12 O43570 4/20 0.41
▸ CA1 P00915 4/20 0.41
▸ CA9 Q16790 4/20 0.41
▸ ELANE P08246 1/20 0.34
▸ CYSLTR1 Q9Y271 1/20 0.34
▸ TSHR P16473 1/20 0.33
▸ DRD2 P14416 1/20 0.33
▸ NPBWR1 P48145 1/20 0.33
▸ PTGER4 P35408 1/20 0.33
▸ HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2882151 0.85 PPARA (0.50) PPARAPREPCA12CA1CA9
SCHEMBL14764352 0.84 CA12 (0.52) PPARAPPARGPREPCA12CA1
SCHEMBL6763899 0.83 PREP (0.53) PREPCA12CA1CA9
SCHEMBL12426281 0.82 PREP (0.46) PREPCA12CA1CA9
SCHEMBL1601708 0.82 PREP (0.46) PPARAPPARGPREPCA12CA1
SCHEMBL2675281 0.82 PPARA (0.53) PPARAPREPLTA4HCA12CA1
SCHEMBL9322837 0.82 CA12 (0.50) PPARAPPARGPREPCA12CA1
SCHEMBL13159232 0.81 PPARA (0.48) PPARAPREPLTA4HCA12CA1
SCHEMBL8946199 0.81 PPARA (0.41) PPARAPPARGPREPLTA4HELANE
SCHEMBL6760799 0.81 PREP (0.45) PREPCA12CA1CA9ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239803-A1 SYNTHESIS OF COELENTERAZINE INTERNATIONAL PAPER COMPANY 2024-07-18 — — US claimed
US-11939332-B2 Synthesis of coelenterazine INTERNATIONAL PAPER COMPANY (US) 2024-03-26 — — US claimed
EP-3830088-A1 SYNTHESIS OF COELENTERAZINE International Paper Company (US) 2021-06-09 — — EP claimed
US-20210070762-A1 SYNTHESIS OF COELENTERAZINE INTERNATIONAL PAPER COMPANY (US) 2021-03-11 — — US claimed
CN-112368286-A Synthesis of coelenterazine 国际纸业公司 2021-02-12 — — CN claimed
US-20250388755-A1 PROBE FOR DETECTING CARBAPENEM-RESISTANT BACTERIA AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2025-12-25 — — US disclosed
US-12421393-B2 Probe for detecting carbapenem-resistant bacteria and use thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2025-09-23 — — US disclosed
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF ADAXION THERAPEUTICS, INC. 2025-04-24 — — US disclosed
WO-2025076427-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF OSPREY BIOPHARMACEUTICALS, INC. (US) 2025-04-10 — — WO disclosed
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2024-12-05 — — US disclosed
US-20240239803-A1 SYNTHESIS OF COELENTERAZINE INTERNATIONAL PAPER COMPANY 2024-07-18 — — US disclosed
US-20240239803-A1 SYNTHESIS OF COELENTERAZINE INTERNATIONAL PAPER COMPANY 2024-07-18 — — US disclosed
WO-1999058510-A1 OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-18 — — WO disclosed
US-5849766-A Carbamoyl substituted heterocycles ELI LILLY AND COMPANY (US) 1998-12-15 — — US disclosed
US-5849922-A Preparation of substituted alkenoic acids ELI LILLY AND COMPANY (US) 1998-12-15 — — US disclosed
WO-1998050031-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 — — WO disclosed
EP-0811621-A2 Carbamoyl substituted oxazoles as thromboxane receptor antagonists ELI LILLY AND COMPANY (US) 1997-12-10 — — EP disclosed
US-5686478-A Endothelin antagonists MERCK & CO. INC. (US) 1997-11-11 — — US disclosed
WO-1995003295-A1 ENDOTHELIN ANTAGONISTS MERCK & CO., INC. (US) 1995-02-02 — — WO disclosed
EP-0438873-A1 Inhibitor of ribonucleotide reductase of herpes viruses MERCK & CO. INC. (US) 1991-07-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388755-A1 PROBE FOR DETECTING CARBAPENEM-RESISTANT BACTERIA AND USE THEREOF KLK3, SI, KLK1 PPARA 4793/4885PPARG 4866/4885PREP 512/4885
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF SIGLEC7, SIGLEC9, SELPLG PPARA 2596/4885PPARG 3415/4885PREP 1561/4885
US-12421393-B2 Probe for detecting carbapenem-resistant bacteria and use thereof ABCC1, MGAM, PGLS PPARA 4777/4885PPARG 4845/4885PREP 575/4885
US-11939332-B2 Synthesis of coelenterazine ACHE, UROD, DDT PPARA 3796/4885PPARG 3321/4885PREP 133/4885
US-20240239803-A1 SYNTHESIS OF COELENTERAZINE ACHE, UROD, DDT PPARA 3796/4885PPARG 3321/4885PREP 133/4885
US-20210070762-A1 SYNTHESIS OF COELENTERAZINE ACHE, UROD, DDT PPARA 3796/4885PPARG 3321/4885PREP 133/4885
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME CD47, CD44, CD74 PPARA 3022/4885PPARG 3826/4885PREP 1700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.