Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164006 | 0.98 | CYP19A1 (0.49) | CYP19A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6988243 | 0.76 | HSD17B10 (0.41) | CYP19A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL917244 | 0.71 | CYP19A1 (0.41) | CYP19A1HSD17B10ALDH1A1CYP1A1MAPT | |
| SCHEMBL25292589 | 0.68 | CYP19A1 (0.48) | CYP19A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6051996 | 0.68 | SMN1; SMN2 (0.41) | HSD17B10ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL27678809 | 0.67 | — | — | |
| SCHEMBL28428617 | 0.67 | CTSL (0.42) | HSD17B10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Acetonitrile SCHEMBL8515908 | 0.67 | ALDH1A1 (0.37) | ALDH1A1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL155247 | 0.67 | CYP19A1 (1.00) | CYP19A1CYP1A2CYP3A4CYP2D6CYP1A1 | |
| SCHEMBL6052090 | 0.67 | SMN1; SMN2 (0.40) | HSD17B10ALDH1A1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428696-A | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2017-12-01 | — | — | CN | disclosed |
| EP-3074011-A1 | OCTAHYDRO FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | Corcept Therapeutics, Inc. (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015077530-A1 | OCTAHYDRO FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| US-6828070-B2 | Heat sensitive element | FUJI PHOTO FILM CO., LTD. (JP) | 2004-12-07 | — | — | US | disclosed |