Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322 | 0.91 | NOTUM (0.41) | ALDH1A1NOTUMHMOX1LMNAMAPK1 | |
| Tetrazole SCHEMBL27773444 | 0.78 | KMT2A (0.33) | ALDH1A1NOTUMHMOX1LTA4HKMT2A | |
| SCHEMBL2925661 | 0.68 | NOTUM (0.45) | ALDH1A1NOTUMHMOX1MAPK1KMT2A | |
| SCHEMBL6760836 | 0.67 | CYP19A1 (0.50) | ALDH1A1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL7164006 | 0.66 | CYP19A1 (0.49) | ALDH1A1KMT2AKDM4ENPC1RAB9A | |
| Acetonitrile SCHEMBL28296993 | 0.65 | MAOB (0.44) | ALDH1A1MAPK1L3MBTL1TSHRMAOA | |
| SCHEMBL9633505 | 0.64 | CYP19A1 (0.50) | ALDH1A1LMNAALOX15TSHRTDP1 | |
| Acetonitrile SCHEMBL28305683 | 0.61 | MAOB (0.56) | ALDH1A1ALOX15MAOAMAOBTDP1 | |
| SCHEMBL6988243 | 0.61 | HSD17B10 (0.41) | ALDH1A1TSHRHTTIDO1KMT2A | |
| SCHEMBL11293200 | 0.61 | RAB9A (0.44) | ALDH1A1L3MBTL1ALOX15TSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741503-A1 | RNAI AGENT FOR INHIBITING AGT GENE EXPRESSION AND USE THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2026-05-13 | — | — | EP | disclosed |
| US-20250346902-A1 | RNAI AGENT INHIBITING PCSK9 GENE EXPRESSION AND APPLICATION THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2025-11-13 | — | — | US | disclosed |
| CN-120019147-A | Antisense oligonucleotide for inhibiting trpv1 gene expression and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119816596-A | DsRNA molecule for inhibiting C5 gene expression and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119816597-A | DsRNA molecule for inhibiting HBV gene expression and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119585433-A | RNAi agent for inhibiting AGT gene expression and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119563025-A | DsRNA molecule for inhibiting expression of LP (a) gene and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4464781-A1 | RNAI AGENT INHIBITING PCSK9 GENE EXPRESSION AND APPLICATION THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2024-11-20 | — | — | EP | disclosed |
| CN-118786216-A | RNAi agent for inhibiting PCSK9 gene expression and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118679174-A | Modified nucleoside monomer and double-stranded ribonucleic acid | 石药集团中奇制药技术（石家庄）有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-117580846-A | Compounds with liver targeted delivery effect and oligonucleotide conjugates thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2024019137-A1 | PRODUCTION METHOD OF OLIGONUCLEOTIDE | 住友化学株式会社 | 2024-01-25 | — | — | WO | disclosed |
| WO-2023208106-A1 | COMPOUND HAVING LIVER-TARGETING DELIVERY EFFECT AND OLIGONUCLEOTIDE CONJUGATE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2023-11-02 | — | — | WO | disclosed |
| EP-2458005-A1 | FGF21 CIS-ELEMENT BINDING SUBSTANCE | Galaxy Pharma Inc. (JP) | 2012-05-30 | — | — | EP | disclosed |
| CN-101282986-A | Oligonucleotide analogues incorporating 5-aza-cytosine therein | SUPERGEN INC (US) | 2008-10-08 | — | — | CN | disclosed |