Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL6761925

Cc1c(S)ccc(-c2ccccc2)c1-c1ccccc1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACLY P53396 2/20 0.38
PLK1 P53350 1/20 0.37
PTPN1 P18031 1/20 0.36
MAPT P10636 2/20 0.34
PTGS2 P35354 3/20 0.33
BACE1 P56817 1/20 0.33
AR P10275 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ESR2 Q92731 1/20 0.32
RORC P51449 1/20 0.32
KAT6A Q92794 1/20 0.32
ENPP1 P22413 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL3836982 0.84 PTPN1 (0.40) ACLYPLK1PTPN1MAPTPTGS2
SCHEMBL6761314 0.84 SMN1; SMN2 (0.47) ACLYMAPTPTGS2ESR2KAT6A
Trifluoromethanesulfonic Acid SCHEMBL2429664 0.83 PTPN1 (0.39) ACLYPLK1PTPN1MAPTPTGS2
Trifluoromethanesulfonic Acid SCHEMBL7620408 0.81 ACLY (0.31) ACLY
SCHEMBL6761940 0.81 LMNA (0.42) MAPTPTGS2ALDH1A1HPGD
Trifluoromethanesulfonic Acid SCHEMBL29136447 0.79 PTPN1 (0.38) ACLYPTPN1MAPTPTGS2AR
Trifluoromethanesulfonic Acid SCHEMBL6765037 0.79 PTPN1 (0.38) ACLYPTPN1MAPTPTGS2AR
Trifluoromethanesulfonic Acid SCHEMBL6761225 0.79 PTPN1 (0.43) ACLYPTPN1MAPTPTGS2AR
Trifluoromethanesulfonic Acid SCHEMBL29049220 0.78 PTPN1 (0.47) PLK1PTPN1PTGS2BACE1KAT6A
SCHEMBL6757947 0.77 F2 (0.38) ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1113005-B1 Sulfonium salt compounds WAKO PURE CHEM IND LTD (JP) 2003-08-06 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed