Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL2429664

Fc1c(S)ccc(-c2ccccc2)c1-c1ccccc1.O=S(=O)(O)C(F)(F)F.[NaH]

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.39
PLK1 P53350 1/20 0.35
PTGS2 P35354 5/20 0.34
PTGS1 P23219 2/20 0.34
ACLY P53396 3/20 0.32
ENPP1 P22413 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
CNR1 P21554 1/20 0.31
NR2F2 P24468 1/20 0.31
CNR2 P34972 1/20 0.31
KMT2A Q03164 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
GYS1 P13807 1/20 0.31
KAT6A Q92794 1/20 0.31
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL3836982 0.99 PTPN1 (0.40) PTPN1PLK1PTGS2PTGS1ACLY
Trifluoromethanesulfonic Acid SCHEMBL6761925 0.83 ACLY (0.38) PTPN1PLK1PTGS2ACLYENPP1
Trifluoromethanesulfonic Acid SCHEMBL29049220 0.78 PTPN1 (0.47) PTPN1PLK1PTGS2ENPP1KAT6A
Trifluoromethanesulfonic Acid SCHEMBL29136447 0.74 PTPN1 (0.38) PTPN1PTGS2PTGS1ACLYMEN1
Trifluoromethanesulfonic Acid SCHEMBL6765037 0.74 PTPN1 (0.38) PTPN1PTGS2PTGS1ACLYMEN1
Trifluoromethanesulfonic Acid SCHEMBL28044747 0.72 PTPN1 (0.47) PTPN1PTGS2ENPP1MEN1MAPT
Trifluoromethanesulfonic Acid SCHEMBL3130162 0.72 ENPP1 (0.42) PTPN1PTGS2PTGS1ENPP1
Trifluoromethanesulfonic Acid SCHEMBL28266656 0.72 DNMT1 (0.41) PTPN1ACLYENPP1MEN1MAPT
Biphenyl SCHEMBL1050411 0.72 PTPN1 (0.58) PTPN1MEN1MAPTKMT2AHDAC4
Trifluoromethanesulfonic Acid SCHEMBL3861619 0.71 PTPN1 (0.36) PTPN1PLK1PTGS2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026390-B2 Photoacid generator containing aromatic ring Korea Kumho Petrochenicals Co., Ltd. (KR) 2011-09-27 US disclosed
US-20100113818-A1 Photoacid generator containing aromatic ring KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113818-A1 Photoacid generator containing aromatic ring HAO2, PAH, PPOX PTPN1 1002/4885PLK1 4112/4885PTGS2 2123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.