Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 0.51 |
| ▸ | PGR | P06401 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515555 | 0.89 | SHBG (0.52) | SHBGPGRALDH1A1NR3C1ADRA1A | |
| SCHEMBL7702309 | 0.79 | CYP19A1 (0.63) | SHBGALDH1A1LMNATSHRMAPK1 | |
| Normethandrone SCHEMBL148631 | 0.79 | PGR (0.73) | SHBGPGRALDH1A1NR3C1ADRA1A | |
| Normethandrone SCHEMBL23801610 | 0.79 | PGR (0.73) | SHBGPGRALDH1A1NR3C1ADRA1A | |
| Normethandrone SCHEMBL148632 | 0.79 | PGR (0.73) | SHBGPGRALDH1A1NR3C1ADRA1A | |
| SCHEMBL3225293 | 0.79 | SHBG (0.65) | SHBGPGRALDH1A1NR3C1LMNA | |
| SCHEMBL5550822 | 0.79 | SHBG (0.65) | SHBGPGRALDH1A1NR3C1LMNA | |
| SCHEMBL9948621 | 0.78 | CYP19A1 (0.44) | SHBGALDH1A1LMNACYP3A4CYP2C19 | |
| SCHEMBL23653611 | 0.77 | PGR (0.39) | SHBGPGRALDH1A1NR3C1ADRA1A | |
| SCHEMBL16741271 | 0.76 | SERPINA6 (0.67) | SHBGPGRALDH1A1NR3C1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379253-A1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA,11BETA-DIMETHYL-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2003045398-A1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA, 11BETA-DIMETHY-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-06-05 | — | — | WO | disclosed |