Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SHBG | P04278 | 2/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832271 | 0.87 | CYP19A1 (0.63) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL8083229 | 0.87 | CYP19A1 (0.63) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL3658066 | 0.87 | CYP19A1 (0.63) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL9634417 | 0.85 | CYP19A1 (0.58) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL8209833 | 0.84 | CYP19A1 (0.59) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL9634694 | 0.83 | CYP19A1 (0.58) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL9948621 | 0.81 | CYP19A1 (0.44) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL3660111 | 0.80 | CYP19A1 (0.55) | CYP19A1MAPK1HSD17B10TSHR | |
| SCHEMBL6762657 | 0.79 | SHBG (0.51) | ALDH1A1LMNASHBGMAPK1TSHR | |
| SCHEMBL5550822 | 0.79 | SHBG (0.65) | CYP19A1ALDH1A1LMNASHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212345-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | Akzo Nobel N.V. (NL) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000059920-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | AKZO NOBEL N.V. (NL) | 2000-10-12 | — | — | WO | disclosed |