SCHEMBL676308

SCHEMBL676308

C=Cc1cccc(CC[Si](OC)(OC)OC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
TRPA1 O75762 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
CHRM2 P08172 3/20 0.35
CHRM1 P11229 3/20 0.35
CHRM3 P20309 3/20 0.35
SIGMAR1 Q99720 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
AOC3 Q16853 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11706078 0.91 TP53 (0.40) TP53TDP1CYP4F2CYP4A11TRPA1
SCHEMBL1270787 0.86 TP53 (0.41) TP53TDP1CYP4F2CYP4A11TRPA1
SCHEMBL21247626 0.84 TP53 (0.40) TP53TDP1CYP4F2CYP4A11CHRM2
SCHEMBL29615749 0.83 TP53 (0.44) TP53TDP1CYP4F2CYP4A11TRPA1
SCHEMBL574710 0.82 TAAR1 (0.46) CYP4F2CYP4A11TAAR1CHRM2CHRM1
SCHEMBL16537571 0.82 TP53 (0.35) TP53TDP1CYP4F2CYP4A11
SCHEMBL16537373 0.81 TP53 (0.37) TP53TDP1CYP4F2CYP4A11
SCHEMBL9315480 0.80 TDP1 (0.36) TP53TDP1TRPA1
SCHEMBL16537822 0.80 TP53 (0.33) TP53TDP1CYP4F2CYP4A11MTNR1A
SCHEMBL424493 0.80 ALDH1A1 (0.41) TP53CYP4F2CYP4A11TRPA1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106462011-B Liquid crystal display element, liquid crystal alignment film, and liquid crystal alignment treatment agent 日产化学工业株式会社 2021-11-12 CN disclosed
US-10392523-B2 Non-Newtonian photo-curable ink composition HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2019-08-27 US disclosed
US-20180170789-A1 SELF-SUPPORTED INORGANIC SHEETS, ARTICLES, AND METHODS OF MAKING THE ARTICLES CORNING INCORPORATED 2018-06-21 US disclosed
US-20180170789-A1 SELF-SUPPORTED INORGANIC SHEETS, ARTICLES, AND METHODS OF MAKING THE ARTICLES CORNING INCORPORATED 2018-06-21 US disclosed
US-20170260407-A1 NON-NEWTONIAN PHOTO-CURABLE INK COMPOSITION HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2017-09-14 US disclosed
US-20170260407-A1 NON-NEWTONIAN PHOTO-CURABLE INK COMPOSITION HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2017-09-14 US disclosed
US-20150185512-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-07-02 US disclosed
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2013-01-24 US disclosed
US-8217388-B2 Curable organopolysiloxane composition and semiconductor device DOW CORNING TORAY COMPANY, LTD. (JP) 2012-07-10 US disclosed
CN-101506309-B Curable organopolysiloxane composition and semiconductor device DOW CORNING TORAY CO LTD 2012-03-21 CN disclosed
CN-1993427-B Curable organopolysiloxane composition, method of curing thereof, semiconductor device, and adhesion promoter DOW CORNING TORAY CO LTD 2011-06-22 CN disclosed
US-20110071266-A1 Curable Organopolysiloxane Composition, Method of Curing Thereof, Semiconductor Device, And Adhesion Promotor DOW CORNING TORAY CO., LTD. (JP) 2011-03-24 US disclosed
US-20100301377-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW TORAY CO., LTD. (JP) 2010-12-02 US disclosed
US-7842755-B2 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY COMPANY, LTD. (JP) 2010-11-30 US disclosed
EP-2061840-B1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW CORNING TORAY CO LTD (JP) 2010-01-06 EP disclosed
CN-101506309-A Curable organopolysiloxane composition and semiconductor device DOW CORNING TORAY CO LTD (JP) 2009-08-12 CN disclosed
EP-2061840-A1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2009-05-27 EP disclosed
US-20080262158-A1 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY CO., LTD. (JP) 2008-10-23 US disclosed
WO-2008023537-A1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD (JP) 2008-02-28 WO disclosed
CN-1993427-A Curable organopolysiloxane composition, method of curing thereof, semiconductor device, and adhesion promoter DOW CORNING TORAY CO LTD (JP) 2007-07-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME ZKSCAN2, L1CAM, SDC2 TP53 1405/4885TDP1 3216/4885CYP4F2 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.