SCHEMBL6763115

SCHEMBL6763115

Cc1cn(CCc2ccccn2)cn1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
HRH3 Q9Y5N1 3/20 0.45
HRH1 P35367 1/20 0.44
DAO P14920 1/20 0.44
LMNA P02545 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
ALDH1A1 P00352 1/20 0.44
ALOX15 P16050 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
CNOT7 Q9UIV1 1/20 0.40
QPCT Q16769 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22180834 0.80 QPCT (0.38) QPCT
SCHEMBL27494735 0.75 HSD17B10 (0.54) HSD17B10HRH3HRH1DAOLMNA
SCHEMBL24757074 0.73 ALPL (0.36) QPCT
SCHEMBL8337928 0.73 TBXAS1 (0.54) HSD17B10ALDH1A1ALOX15
SCHEMBL4468564 0.73 KDM4C (0.41) QPCT
SCHEMBL6992439 0.71 QPCT (0.40) QPCT
SCHEMBL31251980 0.70 QPCT (0.48) QPCT
SCHEMBL18912117 0.70 HSD17B10 (0.45) HSD17B10HRH3HRH1DAOLMNA
SCHEMBL230753 0.70 HRH1 (0.73) HSD17B10HRH3HRH1LMNATAAR1
SCHEMBL29485678 0.70 HRH1 (0.73) HSD17B10HRH3HRH1LMNATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4026872-A PHENOLIC CURING AGENTS HITACHI, LTD. (JA) 1977-05-31 US claimed
US-6760989-B2 Decorative badge and method of making DELPHI TECHNOLOGIES, INC. 2004-07-13 US disclosed
US-20030221347-A1 Decorative badge and method of making AUTOLIV DEVELOPMENT AB (SE) 2003-12-04 US disclosed
US-4401499-A LAMINATION SUMITOMO BAKELITE COMPANY LIMITED (JP) 1983-08-30 US disclosed
US-4026872-A PHENOLIC CURING AGENTS HITACHI, LTD. (JA) 1977-05-31 US disclosed
US-4026872-A PHENOLIC CURING AGENTS HITACHI, LTD. (JA) 1977-05-31 US disclosed
US-3984376-A Thermosetting resin compositions prepared from isocyanates and epoxyphenols HITACHI, LTD. (JA) 1976-10-05 US disclosed