Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780049 | 0.85 | SLC5A2 (0.36) | HTR7SLC5A1SLC5A2PDCD1CD274 | |
| SCHEMBL5778171 | 0.85 | MEN1 (0.39) | SLC5A1SLC5A2SCN9APDCD1CD274 | |
| SCHEMBL6763497 | 0.81 | PDCD1 (0.42) | SCN9APDCD1CD274KDM4EMGLL | |
| SCHEMBL6767423 | 0.81 | GRIA1 (0.37) | SLC5A1SLC5A2KDM4EMEN1KMT2A | |
| SCHEMBL5778501 | 0.81 | MAPT (0.42) | PDCD1CD274KDM4ETDP1LMNA | |
| Hydrochloric Acid SCHEMBL5780693 | 0.80 | MAPT (0.41) | PDCD1CD274KDM4ETDP1LMNA | |
| SCHEMBL6767437 | 0.78 | MAPK14 (0.36) | SLC5A1SLC5A2KDM4ELMNAPOLB | |
| Hydrochloric Acid SCHEMBL6765921 | 0.77 | MAPK14 (0.35) | SLC5A1SLC5A2KDM4ELMNAPOLB | |
| SCHEMBL6763493 | 0.69 | ALDH1A1 (0.40) | KDM4ETDP1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6766287 | 0.68 | ALDH1A1 (0.40) | KDM4EALDH1A1GAASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825192-B1 | NON-N-METHYL-D-ASPARTATE (NON- NMDA) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTIC ACTION, FOR EXAMPLE 2-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) RECEPTOR ANTAGONISTIC ACTION | EISAI CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |