Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781166 | 0.89 | HTR7 (0.46) | MAOBHTR1BSMN1; SMN2KDM4EBCHE | |
| Hydrochloric Acid SCHEMBL5782879 | 0.88 | HTR7 (0.45) | MAOBHTR1BSMN1; SMN2KDM4EBCHE | |
| SCHEMBL6772719 | 0.81 | KDM4E (0.41) | LMNAHTR1DHTR1BGAASMN1; SMN2 | |
| SCHEMBL6766055 | 0.78 | CASP6 (0.41) | LMNAMAOBGAAKDM4EL3MBTL1 | |
| SCHEMBL5780812 | 0.78 | HTR7 (0.42) | MAOBHTR1BSMN1; SMN2KDM4EBCHE | |
| SCHEMBL5777171 | 0.77 | POLB (0.52) | MAOBSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL5781445 | 0.77 | HTR7 (0.48) | MAOBHTR1BSMN1; SMN2KDM4EBCHE | |
| Hydrochloric Acid SCHEMBL6765889 | 0.77 | HTR7 (0.41) | MAOBHTR1BSMN1; SMN2KDM4EBCHE | |
| Hydrochloric Acid SCHEMBL5783222 | 0.76 | POLB (0.51) | MAOBSMN1; SMN2KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5785010 | 0.76 | HTR7 (0.47) | MAOBHTR1BSMN1; SMN2KDM4EBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825192-B1 | NON-N-METHYL-D-ASPARTATE (NON- NMDA) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTIC ACTION, FOR EXAMPLE 2-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) RECEPTOR ANTAGONISTIC ACTION | EISAI CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |