Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.58 |
| ▸ | CNR1 | P21554 | 4/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764408 | 0.87 | CNR2 (0.65) | CNR2CNR1ACHEALDH1A1HSD17B10 | |
| SCHEMBL6761965 | 0.81 | CNR2 (0.54) | CNR2CNR1ACHEALDH1A1TSHR | |
| SCHEMBL6767172 | 0.81 | CNR2 (0.68) | CNR2CNR1ACHEALDH1A1HSD17B10 | |
| SCHEMBL6766646 | 0.78 | KDM4E (0.54) | CNR2CNR1ACHEALDH1A1TSHR | |
| SCHEMBL6767192 | 0.77 | CNR2 (0.51) | CNR2CNR1ACHEALDH1A1TSHR | |
| SCHEMBL6762827 | 0.76 | SPHK2 (0.50) | CNR2CNR1ACHEPOLBNPC1 | |
| SCHEMBL3245414 | 0.75 | F2RL3 (0.67) | ALDH1A1TSHRF2RL3HSD17B10MAPK1 | |
| SCHEMBL8415795 | 0.74 | CNR1 (0.61) | CNR2CNR1ACHEALDH1A1TSHR | |
| SCHEMBL5430238 | 0.73 | F2RL3 (0.64) | CNR2CNR1ACHEALDH1A1F2RL3 | |
| SCHEMBL8007567 | 0.72 | CNR2 (0.68) | CNR2CNR1ACHEALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048866-A1 | Indazole derivatives that are activators of soluble guanylate cyclase | ABBOTT LABORATORIES | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048866-A1 | Indazole derivatives that are activators of soluble guanylate cyclase | GUCY1B1, GUCY1A1, GUCY1A2 | CNR2 1561/4885CNR1 1179/4885ACHE 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.