SCHEMBL676399

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL675835	0.86	POLB (0.37)	CYP1A2CYP1A1CYP1B1DPP4MEN1
	SCHEMBL675214	0.86	PDE4D (0.36)	CYP1A2CYP1A1CYP2D6CYP1B1DPP4
	SCHEMBL5942672	0.81	TSHR (0.39)	DPP4MEN1KMT2AKDM4EMAPT
	SCHEMBL16782522	0.80	BPTF (0.39)	CYP1A2CYP1A1CYP2D6CYP1B1DPP4
	SCHEMBL676115	0.80	TNFRSF1A (0.37)	CYP1A2CYP1A1CYP2D6CYP1B1DPP4
	SCHEMBL675858	0.80	SMN1; SMN2 (0.38)	CYP1A2CYP1A1CYP2D6CYP1B1DPP4
	SCHEMBL674643	0.78	HPGD (0.36)	DPP4MEN1KMT2AKDM4EALDH1A1
	SCHEMBL29814930	0.76	HPGD (0.35)	MEN1KMT2AALDH1A1MAPTSMN1; SMN2
	SCHEMBL29419084	0.76	PTPN1 (0.37)	MEN1KMT2AKDM4EALDH1A1MAPT
	SCHEMBL675920	0.76	MAPT (0.35)	DPP4MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.