SCHEMBL674643

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL676180	0.87	KRAS (0.34)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL675835	0.85	POLB (0.37)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL675920	0.82	MAPT (0.35)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL5942284	0.81	NNMT (0.36)	POLBMAPTKMT2ACYP3A4PTPN1
	SCHEMBL27813524	0.81	ACHE (0.45)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL6149583	0.80	CYP3A4 (0.46)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL28332848	0.79	POLB (0.36)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL676399	0.78	CYP1A2 (0.37)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL12998810	0.77	PTPN1 (0.41)	HPGDPOLBMAPTKMT2AMEN1
	SCHEMBL6308161	0.77	KRAS (0.46)	HPGDPOLBMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.