SCHEMBL675920

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL675835	0.83	POLB (0.37)	MAPTKMT2ACYP3A4POLBHPGD
	SCHEMBL5942210	0.82	LMNA (0.36)	KMT2ACYP3A4POLBALDH1A1HTT
	SCHEMBL674643	0.82	HPGD (0.36)	MAPTKMT2ACYP3A4POLBHPGD
	SCHEMBL27813524	0.79	ACHE (0.45)	MAPTKMT2ACYP3A4POLBHPGD
	SCHEMBL6149583	0.78	CYP3A4 (0.46)	MAPTKMT2ACYP3A4POLBHPGD
	SCHEMBL4595459	0.77	LMNA (0.35)	MAPTKMT2ACYP3A4MEN1ALDH1A1
	SCHEMBL676399	0.76	CYP1A2 (0.37)	MAPTKMT2ACYP3A4POLBHPGD
	SCHEMBL12998810	0.76	PTPN1 (0.41)	MAPTKMT2ACYP3A4POLBHPGD
	SCHEMBL6245601	0.74	PTPN1 (0.39)	MAPTKMT2ACYP3A4POLBHPGD
	SCHEMBL6247176	0.74	KMT2A (0.36)	MAPTKMT2ACYP3A4POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.