Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.51 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450275 | 0.91 | KIT (0.64) | KITALDH1A1EPHX2L3MBTL1NPSR1 | |
| SCHEMBL13450228 | 0.90 | SMN1; SMN2 (0.56) | KITMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2236934 | 0.89 | LMNA (0.55) | KITMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL13403410 | 0.89 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2NAMPTCYP2D6CYP2C9 | |
| SCHEMBL13403409 | 0.81 | KDM4E (0.55) | KITALDH1A1GAAEPHX2L3MBTL1 | |
| SCHEMBL22874354 | 0.79 | HDAC1 (0.51) | MAPTRECQLEPHX2NAMPT | |
| SCHEMBL9199198 | 0.79 | LMNA (0.67) | MAPTRECQLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10730956 | 0.78 | EPHX2 (0.59) | SMN1; SMN2HTTEPHX2L3MBTL1 | |
| SCHEMBL2955185 | 0.78 | MAPT (0.60) | MAPTRECQLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14430781 | 0.77 | HPGDS (0.54) | MAPTRECQLEPHX2NAMPTSMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063725-A1 | Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use | LABORATORIES FOURNIER S.A. (FR) | 2004-04-01 | — | — | US | disclosed |
| EP-1351928-A2 | NOVEL N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER S.A. (FR) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002053516-A2 | N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER SA (FR) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063725-A1 | Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use | GLS, GLS2, GLRB | KIT 579/4885MAPT 1262/4885RECQL 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.