Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109157 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL28883906 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL30456186 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL3477839 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL7139457 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL3397908 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL7706359 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL3721835 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL535669 | 1.00 | KMT2A (0.50) | KMT2ACA1CA2CA4MT-CO2 | |
| SCHEMBL3438194 | 0.97 | CA1 (0.48) | KMT2ACA1CA2CA4MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202186-A | 3-Ethylamino-indole dimers as serotonergic agents for the treatment of diseases associated therewith | 思维模式制药公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-120091999-A | 3-Pyrrolidine-indole dimers as serotonergic agents for the treatment of related disorders | 思维模式制药公司 | 2025-06-03 | — | — | CN | disclosed |
| US-20240294520-A1 | AMINO ACID COMPOUNDS WITH UNBRANCHED LINKERS AND METHODS OF USE | PLIANT THERAPEUTICS INC (US) | 2024-09-05 | — | — | US | disclosed |
| CN-112689507-B | Amino acid compounds having unbranched linkers and methods of use thereof | 普利安特治疗公司 | 2024-07-30 | — | — | CN | disclosed |
| US-20240166630-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-05-23 | — | — | US | disclosed |
| US-20240166599-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-05-23 | — | — | US | disclosed |
| US-20240051978-A1 | 3-CYCLIC AMINE-INDOLE DERIVATIVES AS SEROTONERGIC AGENTS FOR THE TREATMENT OF CNS DISORDERS | MINDSET PHARMA INC. (CA) | 2024-02-15 | — | — | US | disclosed |
| WO-2024026574-A1 | 3-PYRROLIDINE-INDOLE DIMERS AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-02-08 | — | — | WO | disclosed |
| WO-2024026573-A1 | 3-ETHYLAMINO-INDOLE DIMERS AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-02-08 | — | — | WO | disclosed |
| CN-117500788-A | Indole derivatives as serotonergic agents for the treatment of diseases associated therewith | 明德赛特制药公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-0574185-B1 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORP (UY) | 1997-09-03 | — | — | EP | disclosed |
| US-5475021-A | Administering N-substituted succinimides | VANDERBILT UNIVERSITY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1995015163-A1 | NOVEL COMPOUNDS FOR INHIBITION OF CYCLOOXYGENASE ACTIVITY | VANDERBILT UNIVERSITY (US) | 1995-06-08 | — | — | WO | disclosed |
| EP-0574185-A2 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORPORATION (UY) | 1993-12-15 | — | — | EP | disclosed |
| EP-0388188-A1 | Benzoxepin derivatives | SUNTORY LIMITED (JP) | 1990-09-19 | — | — | EP | disclosed |
| EP-0100900-B1 | NOVEL (3.2.0.) BICYCLOHEPTANONE OXIME ETHERS WITH VALUABLE THERAPEUTIC PROPERTIES | SYNTEX (U.S.A.) INC. (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4552898-A | CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-11-12 | — | — | US | disclosed |
| US-4515972-A | Intermediates and method for producing intermediates useful in the preparation of 7-oxabicycloheptane prostaglandin derivatives | E. R. SQUIBB & SONS, INC. (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0100900-A1 | Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4423068-A | (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1983-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166599-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | TPH1, TPH2, HTR3A | KMT2A 2664/4885CA1 3421/4885CA2 4143/4885 |
| US-20240294520-A1 | AMINO ACID COMPOUNDS WITH UNBRANCHED LINKERS AND METHODS OF USE | ITGA2B, ITGB6, ITGB1 | KMT2A 1467/4885CA1 4313/4885CA2 4198/4885 |
| US-20240166630-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | TPH1, TPH2, HTR3A | KMT2A 3295/4885CA1 3713/4885CA2 4265/4885 |
| US-20240051978-A1 | 3-CYCLIC AMINE-INDOLE DERIVATIVES AS SEROTONERGIC AGENTS FOR THE TREATMENT OF CNS DISORDERS | TPH1, TPH2, HTR3A | KMT2A 2669/4885CA1 3541/4885CA2 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.