SCHEMBL6764913

SCHEMBL6764913

CCCCCCCCCCCCCCCCCC(=O)[C](C(=O)CCCCCCCCCCCCCCCCC)C(O)CO

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.58
CES1 P23141 4/20 0.58
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757863 1.00 CES2 (0.58) CES2CES1KDM4EDUSP3MEN1
SCHEMBL6761739 1.00 CES2 (0.58) CES2CES1KDM4EDUSP3MEN1
SCHEMBL6757875 0.90 FAAH (0.58) DUSP3MEN1KMT2ALMNAMAPT
SCHEMBL3621423 0.86 CES2 (0.60) CES2CES1
SCHEMBL4778226 0.86 CES2 (0.60) CES2CES1
SCHEMBL16449208 0.84 CES2 (0.58) CES2CES1KDM4EDUSP3MEN1
SCHEMBL16449209 0.84 CES2 (0.58) CES2CES1KDM4EDUSP3MEN1
SCHEMBL16449177 0.84 CES2 (0.58) CES2CES1KDM4EDUSP3MEN1
SCHEMBL16449174 0.84 CES2 (0.58) CES2CES1KDM4EDUSP3MEN1
SCHEMBL16449175 0.82 CES2 (0.56) CES2CES1KDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444660-B1 DEXAMETHASONE COVALENTLY BONDED TO A LIPID MOIETY VIA A LINKING GROUP IMARX THERAPEUTICS, INC. 2002-09-03 US claimed
WO-1998050040-A1 NOVEL LIPID SOLUBLE STEROID PRODRUGS IMARX PHARMACEUTICAL CORP. (US) 1998-11-12 WO claimed
WO-2024133635-A1 COMPOSITION BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) 2024-06-27 WO disclosed
US-6716412-B2 LYSIS BLOOD CLOTS IMARX THERAPEUTICS, INC. 2004-04-06 US disclosed
US-6548047-B1 Using lecithin, cephalin filled with gases; scanning; medical diagnosis BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. 2003-04-15 US disclosed
US-6444660-B1 DEXAMETHASONE COVALENTLY BONDED TO A LIPID MOIETY VIA A LINKING GROUP IMARX THERAPEUTICS, INC. 2002-09-03 US disclosed
US-20010031243-A1 Novel methods of ultrasound treatment using gas or gaseous precursor-filled compositions IMARX PHARMACEUTICAL CORP. 2001-10-18 US disclosed
US-6090800-A REACTION PRODUCT CONTAINING DEXAMETHASONE IMARX PHARMACEUTICAL CORP. (US) 2000-07-18 US disclosed
EP-0901793-A1 Thermal preactivation of gaseous precursor filled compositions IMARX PHARMACEUTICAL CORP. (US) 1999-03-17 EP disclosed
WO-1998050040-A1 NOVEL LIPID SOLUBLE STEROID PRODRUGS IMARX PHARMACEUTICAL CORP. (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031243-A1 Novel methods of ultrasound treatment using gas or gaseous precursor-filled compositions SON, HYOU1, GCG CES2 1877/4885CES1 2467/4885KDM4E 4508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.