Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 10/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.55 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.55 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.55 |
| ▸ | GAPDH | P04406 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761689 | 0.92 | DNPH1 (0.66) | DNPH1ADORA3ADORA2AADORA1SLC29A1 | |
| SCHEMBL6760523 | 0.86 | DNPH1 (0.73) | DNPH1ADORA3MAPK1STAT6SMN1; SMN2 | |
| SCHEMBL6765355 | 0.85 | SLC29A1 (0.66) | DNPH1DPP4MEN1SLC28A1MAP3K7 | |
| SCHEMBL7030062 | 0.85 | SLC29A1 (0.58) | DNPH1ADORA3ADORA2AADORA1STAT6 | |
| SCHEMBL6760682 | 0.84 | ADK (0.63) | DNPH1DPP4MEN1SLC28A1MAP3K7 | |
| SCHEMBL6423141 | 0.84 | DNPH1 (0.71) | DNPH1DPP4MEN1SLC28A1MAP3K7 | |
| SCHEMBL6758946 | 0.84 | DNPH1 (0.71) | DNPH1DPP4MEN1SLC28A1MAP3K7 | |
| SCHEMBL6761653 | 0.83 | DNPH1 (0.74) | DNPH1DPP4MEN1SLC28A1MAP3K7 | |
| SCHEMBL6760662 | 0.82 | DNPH1 (0.69) | DNPH1DPP4ADORA3MAPK1STAT6 | |
| SCHEMBL6763303 | 0.82 | SLC29A1 (0.68) | DNPH1DPP4MEN1SLC28A1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110718-A1 | Anti-HCV nucleoside derivatives | DEVOS RENE (GB) | 2004-06-10 | — | — | US | claimed |
| CN-1466591-A | Nucleoside derivatives | - | 2004-01-07 | — | — | CN | claimed |
| US-20030008841-A1 | Anti-HCV nucleoside derivatives | F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) | 2003-01-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008841-A1 | Anti-HCV nucleoside derivatives | PNP, HAVCR2, NUDT14 | DNPH1 1216/4885DPP4 124/4885MEN1 4883/4885 |
| US-20040110718-A1 | Anti-HCV nucleoside derivatives | PNP, HAVCR2, NUDT14 | DNPH1 1216/4885DPP4 124/4885MEN1 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.