Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | MC3R | P41968 | 1/20 | 0.55 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186159 | 0.84 | KDM4E (0.70) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL5261595 | 0.80 | KMT2A (0.58) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL4019791 | 0.76 | KMT2A (0.63) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL30593013 | 0.76 | KMT2A (0.63) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL7618500 | 0.75 | KDM4E (0.70) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL4901021 | 0.74 | KDM4E (0.47) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL24977120 | 0.74 | KMT2A (0.67) | KDM4ENAPRTHDAC3HDAC1HDAC2 | |
| SCHEMBL10373456 | 0.74 | P2RX7 (0.52) | KDM4ENAPRTTSHRHDAC8SMN1; SMN2 | |
| SCHEMBL2536804 | 0.73 | — | — | |
| Pyrazinoic Acid SCHEMBL29651929 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102465-A1 | Pyrazolyl pyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-05-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102465-A1 | Pyrazolyl pyrimidines | ZYX, P2RX5, P2RX1 | KDM4E 3833/4885NAPRT 1496/4885HCAR2 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.