Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66048 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL1963633 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782982 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL338159 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9271352 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782992 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782989 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL676573 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782996 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782987 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813592-B1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-10-10 | — | — | EP | claimed |
| US-7872148-B2 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-18 | — | — | US | claimed |
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-08 | — | — | US | claimed |
| EP-1813592-A1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2007-08-01 | — | — | EP | claimed |
| EP-1813592-B1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-7872148-B2 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1813592-A1 | CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012318-A1 | Cage-shaped cyclobutanoic dianhydrides and process for production thereof | ADH1C, ADH1A, ADH5 | POLB 249/4885TDP1 2154/4885CTDSP1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.