Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 13/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765424 | 0.91 | F2 (0.55) | F2PRSS1PRSS2PRSS3MGAT2 | |
| SCHEMBL6762119 | 0.85 | TMPRSS6 (0.57) | ALDH1A1HPGDF2PRSS1PRSS2 | |
| SCHEMBL6571783 | 0.84 | LMNA (0.51) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL6767804 | 0.83 | SMN1; SMN2 (0.54) | MAPTF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6771025 | 0.83 | F2 (0.55) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6766786 | 0.83 | F2 (0.60) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6765337 | 0.81 | F2 (0.52) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6771080 | 0.81 | F2 (0.51) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6764616 | 0.80 | SLC22A12 (0.44) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6764877 | 0.79 | F2 (0.57) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | NAT1, CYP3A5, CYP3A7 | ALDH1A1 669/4885MAPT 449/4885HPGD 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.