Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 12/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765424 | 0.86 | F2 (0.55) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6765892 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2MAPK1MEN1KMT2AF2 | |
| SCHEMBL6574325 | 0.83 | LMNA (0.44) | SMN1; SMN2LMNAGAAMAPK1HTT | |
| SCHEMBL6766786 | 0.82 | F2 (0.60) | HTTF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6764616 | 0.81 | SLC22A12 (0.44) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6762119 | 0.80 | TMPRSS6 (0.57) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6765337 | 0.79 | F2 (0.52) | F2PRSS1PRSS2PRSS3PLAU | |
| SCHEMBL6764538 | 0.79 | F2 (0.43) | SMN1; SMN2LMNAGAAMAPK1MEN1 | |
| SCHEMBL6771025 | 0.78 | F2 (0.55) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6762034 | 0.76 | F2 (0.41) | LMNAF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | NAT1, CYP3A5, CYP3A7 | SMN1; SMN2 2628/4885LMNA 1447/4885GAA 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.