Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769131 | 0.96 | HRH3 (0.43) | HRH3HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL6890251 | 0.84 | F10 (0.38) | ALDH1A1MEN1KMT2AF10KDM4E | |
| SCHEMBL6770185 | 0.84 | TBXAS1 (0.36) | HPGDALDH1A1SMN1; SMN2F10KDM4E | |
| SCHEMBL6771054 | 0.82 | MLYCD (0.37) | HRH3HPGDALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6765882 | 0.80 | F10 (0.56) | HRH3HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL6775235 | 0.80 | TBXAS1 (0.36) | HRH3HPGDALDH1A1SMN1; SMN2F10 | |
| Trifluoroacetic Acid SCHEMBL6769129 | 0.80 | F10 (0.53) | HRH3HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3901372 | 0.79 | F10 (0.64) | F10 | |
| SCHEMBL5105097 | 0.78 | F10 (0.62) | F10 | |
| Trifluoroacetic Acid SCHEMBL7812384 | 0.72 | F10 (0.40) | HRH3F10C1SMAPK7KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |