Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379137 | 0.82 | DAO (0.46) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL6766403 | 0.82 | LMNA (0.37) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL6766585 | 0.81 | GRIN2D (0.51) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL6767940 | 0.80 | GRIN2D (0.43) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL26556169 | 0.79 | ADRB2 (0.40) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL6766534 | 0.78 | BRAF (0.41) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL6773041 | 0.77 | KDM4E (0.49) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL5388796 | 0.77 | DAO (0.50) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL6768030 | 0.77 | GRIN2D (0.45) | DRD2DRD4DRD3GRIN2DGRIN3B | |
| SCHEMBL6767772 | 0.77 | GRIN2D (0.45) | DRD2DRD4DRD3GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |