Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766403 | 0.82 | LMNA (0.37) | BRAFDRD2DRD4DRD3GRIN2D | |
| SCHEMBL6766689 | 0.78 | GRIN2D (0.38) | KDM4EBRAFDRD2DRD4DRD3 | |
| SCHEMBL6766041 | 0.77 | DRD2 (0.42) | KDM4EMAPTDRD2DRD4DRD3 | |
| SCHEMBL6767054 | 0.76 | GRIN2D (0.36) | KDM4EBRAFDRD2DRD4DRD3 | |
| SCHEMBL6768396 | 0.74 | GRIN2D (0.41) | KDM4EPOLBMAPTDRD2DRD4 | |
| SCHEMBL5379137 | 0.73 | DAO (0.46) | KDM4EDRD2DRD4DRD3GRIN2D | |
| SCHEMBL6773049 | 0.73 | GRIN2D (0.41) | KDM4EBRAFDRD2DRD4DRD3 | |
| SCHEMBL6766534 | 0.72 | BRAF (0.41) | PARP14BRAFDRD2DRD4DRD3 | |
| SCHEMBL6773618 | 0.72 | GRIN2D (0.40) | KDM4EMAPTBRAFDRD2DRD4 | |
| SCHEMBL6763596 | 0.71 | MAPT (0.63) | KDM4EPOLBHTTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |