⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065389 | 0.78 | — | — | |
| SCHEMBL18312132 | 0.78 | — | — | |
| SCHEMBL11129844 | 0.78 | — | — | |
| SCHEMBL134304 | 0.74 | TSHR (0.65) | — | |
| SCHEMBL8413065 | 0.74 | — | — | |
| SCHEMBL11849588 | 0.74 | CHRNB2 (0.50) | — | |
| SCHEMBL14495121 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL10840395 | 0.72 | TSHR (0.50) | — | |
| SCHEMBL7536149 | 0.72 | CHRNB2 (0.48) | — | |
| SCHEMBL4263485 | 0.72 | TSHR (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565602-A | REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| US-20230115184-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-20160374945-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUG AND NEUTRAL POLYMERS | BEND RESEARCH, INC. (US) | 2016-12-29 | — | — | US | disclosed |
| US-9468604-B2 | Pharmaceutical compositions of dispersions of drug and neutral polymers | BEND RESEARCH, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20140210117-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUG AND NEUTRAL POLYMERS | BEND RESEARCH, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8703199-B2 | Pharmaceutical compositions of adsorbates of amorphous drug | BEND RESEARCH, INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-8389011-B2 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors | BEND RESEARCH, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389006-B2 | Pharmaceutical compositions of adsorbates of amorphous drug | BEND RESEARCH, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120295988-A1 | Pharmaceutical Compositions of Dispersions of Amorphous Drugs Mixed with Polymers | BEND RESEARCH, INC. | 2012-11-22 | — | — | US | disclosed |
| US-20120277315-A1 | PHARMACEUTICAL COMPOSITIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | BEND RESEARCH, INC. | 2012-11-01 | — | — | US | disclosed |
| US-8197848-B2 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors | BEND RESEARCH, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8173142-B2 | Pharmaceutical compositions of drugs and neutralized acidic polymers | BEND RESEARCH, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-8147872-B2 | Pharmaceutical compositions of drugs and neutralized acidic polymers | Bend Reseach, Inc. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8048452-B2 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitor | BEND RESEARCH, INC. (US) | 2011-11-01 | — | — | US | disclosed |
| US-7897175-B2 | Cholesteryl ester transfer protein (CETP) such as torcetrapib; 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase); two drugs are separate from each other; improved chemical stability of the HMG-CoA reductase inhibitor | BEND RESEARCH, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7887840-B2 | Bioavailability of low- solubility drugs | BEND RESEARCH, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| US-20090011024-A1 | Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers | PFIZER INC. | 2009-01-08 | — | — | US | disclosed |
| US-20080292707-A1 | Pharmaceutical Compositions of Adsorbates of Amorphous Drug | PFIZER INC | 2008-11-27 | — | — | US | disclosed |
| US-20070282009-A1 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors | PFIZER INC | 2007-12-06 | — | — | US | disclosed |
| US-20070148236-A1 | Pharmaceutical Compositions of Adsorbates of Amorphous Drug | PFIZER PRODUCTS INC. | 2007-06-28 | — | — | US | disclosed |