Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770014 | 0.90 | TDP1 (0.41) | TDP1KAT2BBAZ2BSLC6A3PDE4B | |
| SCHEMBL6654536 | 0.89 | TDP1 (0.39) | TDP1KAT2BBAZ2BSLC6A3PDE4B | |
| SCHEMBL7221126 | 0.88 | TDP1 (0.37) | TDP1KAT2BBAZ2BSLC6A3PDE4B | |
| SCHEMBL8402440 | 0.86 | TP53 (0.36) | TDP1KAT2BBAZ2BSLC6A3PDE4B | |
| SCHEMBL8954676 | 0.84 | TDP1 (0.44) | TDP1KAT2BBAZ2BSLC6A3PDE4B | |
| SCHEMBL7513173 | 0.82 | TDP1 (0.42) | TDP1KAT2BBAZ2BSLC6A3PDE4B | |
| SCHEMBL9535725 | 0.78 | KDM4E (0.44) | TDP1KAT2BBAZ2BSLC6A3KDM4E | |
| SCHEMBL8370615 | 0.77 | DHFR (0.35) | TDP1KAT2BBAZ2BHIF1ASLC6A3 | |
| SCHEMBL8954773 | 0.77 | DHFR (0.35) | TDP1KAT2BBAZ2BHIF1ASLC6A3 | |
| SCHEMBL7215176 | 0.77 | KAT2B (0.40) | TDP1KAT2BBAZ2BSLC6A3PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730799-B2 | O-HYDROXYETHYL-O'-METHYL-BENZOFURANDIONE DIOXIMES ARE REARRANGED IN THE PRESENCE OF A DILUENT AND IN THE PRESENCE OF AN ACID OR A BASE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-04 | — | — | US | disclosed |
| US-20020169316-A1 | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | US | disclosed |
| US-6479675-B1 | Processes for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
| US-6437153-B1 | O-HYDROXYETHYL-O'-ALKYLBENZOFURANDIONE DIOXIMES REARRANGED IN THE PRESENCE OF A DILENT, AN ACID OR A BASE; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-04-25 | — | — | US | disclosed |
| US-6335454-B1 | FUNGICIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| US-6150521-A | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-21 | — | — | US | disclosed |
| US-6093837-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-25 | — | — | US | disclosed |
| US-6005104-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES; PREPARED BY REARRANGING O-HYDROXYETHYL-O'-ALKYL-BENZOFURANDIONE DIOXIMES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| US-5883250-A | ARYL SUBSTITUTED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| US-5679676-A | Substituted azadioxacycloalkenes and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | DDT, CYP4Z1, CYP51A1 | TDP1 546/4885KAT2B 4018/4885BAZ2B 2458/4885 |
| US-20020169316-A1 | Process for preparing 3-(1-hydroxyphenyl-1-alkoximinomethyl) dioxazines | CYP4Z1, CYP4X1, CYP51A1 | TDP1 478/4885KAT2B 4567/4885BAZ2B 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.