Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763570 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAHSD17B10PDE3B | |
| SCHEMBL6772924 | 0.86 | PKM (0.51) | ALDH1A1KDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL6767981 | 0.83 | IAPP (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2CYP1A2 | |
| SCHEMBL6767964 | 0.81 | EGFR (0.45) | KDM4EPDE3BPDE3AP2RY12SMN1; SMN2 | |
| SCHEMBL6773027 | 0.81 | KMT2A (0.44) | ALDH1A1KDM4EMAPTLMNAHSD17B10 | |
| SCHEMBL6772930 | 0.79 | GRIN2D (0.45) | PDE3BPDE3AP2RY12CYP1A2GRIN2D | |
| SCHEMBL6768134 | 0.78 | NLRP3 (0.41) | ALDH1A1GAAKDM4ELMNAHSD17B10 | |
| SCHEMBL6763616 | 0.78 | GRIN2D (0.46) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL5388796 | 0.78 | DAO (0.50) | ALDH1A1KDM4ELMNACYP1A2GRIN2D | |
| SCHEMBL6763648 | 0.77 | PDE3B (0.40) | ALDH1A1LMNAPDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |