SCHEMBL6766429

SCHEMBL6766429

CC(C)(c1c(Cl)cc(O)cc1Cl)c1c(Cl)cc(O)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.50
HPGD P15428 5/20 0.50
CYP3A4 P08684 3/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
CHRM1 P11229 1/20 0.40
ALOX15 P16050 1/20 0.40
MAOA P21397 1/20 0.40
TBXA2R P21731 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
BACE1 P56817 1/20 0.35
TSHR P16473 4/20 0.35
ESR1 P03372 3/20 0.35
ESR2 Q92731 2/20 0.35
AR P10275 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10936836 0.84 HSD17B10 (0.50) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL29575152 0.74 HSD17B10 (0.46) HSD17B10HPGDCYP3A4CHRM1ALOX15
SCHEMBL900980 0.73 CYP3A4 (0.31) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL23641632 0.72 GABRA1 (0.43) HSD17B10HPGDCYP3A4GABRA1GABRB2
SCHEMBL29295830 0.72 ALOX15 (0.39) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL2886053 0.70 CYP3A4 (0.48) HSD17B10HPGDCYP3A4GABRA1GABRB2
SCHEMBL24663908 0.70 CYP3A4 (0.48) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL83132 0.69 CYP3A4 (0.58) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL1549248 0.69 HSD17B10 (0.52) HSD17B10HPGDCYP3A4CRHBPCRHR2
SCHEMBL17693529 0.69 HSD17B10 (0.56) HSD17B10HPGDCYP3A4CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0391303-B1 Color filter array element with polycarbonate receiving layer EASTMAN KODAK CO (US) 1995-03-22 EP claimed
EP-0391303-A2 Color filter array element with polycarbonate receiving layer EASTMAN KODAK COMPANY (US) 1990-10-10 EP claimed
US-4962081-A MULTICOLOR MOSAIC PATTERN EASTMAN KODAK COMPANY (US) 1990-10-09 US claimed
US-6734263-B2 POLYMERIC MATERIAL AND A PROCESS FOR MAKING THE POLYMERIC MATERIAL. THE POLYMERIC MATERIAL HAS ADHESIVE AND NOISE ABATEMENT PROPERTIES OVER A BROAD TEMPERATURE RANGE. FURTHER, THE MATERIAL IS CHIP AND CORROSION RESISTANT AND PROVIDES DIVERSIFIED CHEMICAL TECHNOLOGIES, INC. 2004-05-11 US disclosed
US-20040068062-A1 Hydroxyaliphatic functional epoxy resins WALKER LOUIS L (US) 2004-04-08 US disclosed
US-6613849-B2 Curable multifunctional glycidyl ethers and acrylated derivatives thereof, for example the diglycidyl ether of 1,2-bis(4-hydroxyphenyl)-2-hydroxypropane; thermosetting resins; higher reactivity during curing THE DOW CHEMICAL COMPANY 2003-09-02 US disclosed
US-20030119987-A1 Non-polyvinyl chloride, interpenetrating network epoxy/urethane acrylates DIVERSIFIED CHEMICAL TECHNOLOGIES, INC. (US) 2003-06-26 US disclosed
US-20020091223-A1 Hydroxyaliphatic functional epoxy resins WALKER LOUIS L (US) 2002-07-11 US disclosed
EP-1216265-A1 HYDROXYALIPHATIC FUNCTIONAL EPOXY RESINS THE DOW CHEMICAL COMPANY (US) 2002-06-26 EP disclosed
US-6353079-B1 DIGLYCIDYL ETHER OF BISPHENOL CONTAINING HYDROXYALIPHATIC GROUP LINKAGE BETWEEN TWO AROMATIC RINGS OF BISPHENOL THE DOW CHEMICAL COMPANY 2002-03-05 US disclosed
WO-2001009220-A1 HYDROXYALIPHATIC FUNCTIONAL EPOXY RESINS THE DOW CHEMICAL COMPANY (US) 2001-02-08 WO disclosed
US-4988665-A THERMAL TRANSFER SYSTEMS, MULTILAYER ELEMENTS WITH RADIATION TRANSPARENT SUPPORTS EASTMAN KODAK COMPANY (US) 1991-01-29 US disclosed
US-4975410-A Thermally-transferred color filter array element and process for preparing EASTMAN KODAK COMPANY (US) 1990-12-04 US disclosed
EP-0399473-A1 Mixture of yellow and cyan dyes to form a green hue for color filter array element EASTMAN KODAK COMPANY (US) 1990-11-28 EP disclosed
EP-0398324-A1 Arylazoaniline blue dyes for color filter array element EASTMAN KODAK COMPANY (US) 1990-11-22 EP disclosed
EP-0393580-A1 Mixture of yellow and magenta dyes to form a red hue for color filter array element EASTMAN KODAK COMPANY (US) 1990-10-24 EP disclosed
US-4957898-A Mixture of yellow and magenta dyes to form a red hue for color filter array element EASTMAN KODAK COMPANY (US) 1990-09-18 US disclosed
EP-0026121-B1 PROCESS FOR PREPARING POLYARYLATES IN THE PRESENCE OF A DIPHENYL ETHER COMPOUND AND A MAGNESIUM CATALYST UNION CARBIDE CORPORATION (US) 1986-06-18 EP disclosed
US-4296232-A ESTERIFICATION OR ESTER INTERCHANGE UNION CARBIDE CORPORATION (US) 1981-10-20 US disclosed
EP-0026121-A1 Process for preparing polyarylates in the presence of a diphenyl ether compound and a magnesium catalyst UNION CARBIDE CORPORATION (US) 1981-04-01 EP disclosed