SCHEMBL900980

SCHEMBL900980

CC(C)(C1=CC=C(O)CC1(Cl)Cl)c1c(Cl)cc(O)cc1Cl

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6766429 0.73 HSD17B10 (0.50) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL900946 0.69 ALDH1A1 (0.31) CYP3A4HPGDHSD17B10
SCHEMBL10936836 0.65 HSD17B10 (0.50) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL29295830 0.56 ALOX15 (0.39) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL23043288 0.54 HSD17B10 (0.41) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL30034058 0.54 HSD17B10 (0.41) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL24663908 0.54 CYP3A4 (0.48) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL2036113 0.53 HSD17B10 (0.58) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL83132 0.53 CYP3A4 (0.58) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL1549248 0.53 HSD17B10 (0.52) CYP3A4HPGDCRHBPCRHR2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9340702-B2 Coating compositions BLUE CUBE IP LLC (US) 2016-05-17 US disclosed
US-9284434-B2 Epoxy resin compositions BLUE CUBE IP LLC (US) 2016-03-15 US disclosed
EP-2621990-B1 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM BLUE CUBE IP LLC (US) 2016-02-24 EP disclosed
US-9068039-B2 Thermosettable compositions and thermosets therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2015-06-30 US disclosed
US-9006312-B2 Composite compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-14 US disclosed
US-20150099831-A1 COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-09 US disclosed
US-8937114-B2 Coating compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-20 US disclosed
US-8937145-B2 Epoxy resin compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-20 US disclosed
US-20140194554-A1 EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-10 US disclosed
EP-2507325-B1 COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-05-21 EP disclosed
US-5510431-A Cure controlled catalyzed mixtures of epoxy resins and curing agents containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1996-04-23 US disclosed
US-5460860-A From curable resin with vicinal epoxide or thiirane groups and curing agent; adhesives, coatings, laminates; highly reflective THE DOW CHEMICAL COMPANY (US) 1995-10-24 US disclosed
US-5458929-A Laminates THE DOW CHEMICAL COMPANY (US) 1995-10-17 US disclosed
US-5412057-A Polyepoxide curing agents THE DOW CHEMICAL COMPANY (US) 1995-05-02 US disclosed
US-5387657-A Liquid crystal polymers; high glass transition temperatures; enhanced unidirectional mechanical properties; coatings, castings, encapsulation, lamination, composites, molding materials THE DOW CHEMICAL COMPANY (US) 1995-02-07 US disclosed
US-5382693-A Curing agents for epoxy resins THE DOW CHEMICAL COMPANY (US) 1995-01-17 US disclosed
WO-1994026690-A1 BIS(AMINOPHENOXY)-ALPHA-SUBSTITUTED STILBENES, CURABLE MIXTURES WITH EPOXY RESINS AND CURED PRODUCTS THE DOW CHEMICAL COMPANY (US) 1994-11-24 WO disclosed
WO-1994025501-A1 EPOXY RESINS CONTAINING THIADIAZOLE AND/OR OXADIAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-11-10 WO disclosed
US-5300594-A Bis(aminophenoxy)-alpha-substituted stilbenes, curable mixtures with epoxy resins and cured products THE DOW CHEMICAL COMPANY (US) 1994-04-05 US disclosed
US-5290887-A Liquid crystal polymers for coatings, castings, encapsulation, electronics or laminates THE DOW CHEMICAL COMPANY (US) 1994-03-01 US disclosed