Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764334 | 0.90 | APP (0.32) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6765056 | 0.88 | ALDH1A1 (0.38) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6765793 | 0.87 | APP (0.34) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6683930 | 0.81 | ALDH1A1 (0.42) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6770716 | 0.76 | APP (0.41) | APPALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL3792911 | 0.75 | APP (0.63) | APPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6684731 | 0.73 | LMNA (0.53) | APPALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL6765076 | 0.72 | — | — | |
| SCHEMBL2190739 | 0.70 | GRIN2D (0.34) | APPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2848562 | 0.70 | GRIN2D (0.46) | ALDH1A1MEN1KMT2AHSD11B1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127715-A1 | Adamantane compounds and insulating film forming coating solutions | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127715-A1 | Adamantane compounds and insulating film forming coating solutions | CHRNA1, ANO1, CHRNA2 | APP 32/4885ALDH1A1 335/4885KDM4E 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.