Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762051 | 0.87 | HSD11B1 (0.33) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6765078 | 0.79 | HSD11B1 (0.35) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6765059 | 0.79 | HSD11B1 (0.36) | HSD11B1P2RX7GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6762003 | 0.77 | NPC1 (0.33) | HSD11B1P2RX7KDM4EMEN1KMT2A | |
| SCHEMBL6850950 | 0.77 | HSD11B1 (0.41) | HSD11B1P2RX7GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6770638 | 0.76 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL6764300 | 0.75 | GRIN2D (0.39) | HSD11B1P2RX7GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6939002 | 0.74 | HSD11B1 (0.42) | HSD11B1P2RX7GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6764330 | 0.74 | GRIN2D (0.31) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6764307 | 0.73 | NPC1 (0.35) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127715-A1 | Adamantane compounds and insulating film forming coating solutions | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127715-A1 | Adamantane compounds and insulating film forming coating solutions | CHRNA1, ANO1, CHRNA2 | HSD11B1 1880/4885P2RX7 1576/4885GRIN2D 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.