Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319389 | 0.78 | MAPT (0.39) | NPC1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6762051 | 0.77 | HSD11B1 (0.33) | MEN1KMT2AHSD11B1 | |
| SCHEMBL6767079 | 0.77 | HSD11B1 (0.41) | KDM4EMEN1KMT2AHSD11B1P2RX7 | |
| SCHEMBL6764307 | 0.76 | NPC1 (0.35) | NPC1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6683930 | 0.76 | ALDH1A1 (0.42) | NPC1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6762049 | 0.72 | NPC1 (0.33) | NPC1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6765059 | 0.71 | HSD11B1 (0.36) | MEN1KMT2AHSD11B1APPP2RX7 | |
| SCHEMBL6764233 | 0.70 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL6765056 | 0.69 | ALDH1A1 (0.38) | NPC1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5898842 | 0.68 | NPC1 (0.35) | NPC1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127715-A1 | Adamantane compounds and insulating film forming coating solutions | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127715-A1 | Adamantane compounds and insulating film forming coating solutions | CHRNA1, ANO1, CHRNA2 | NPC1 696/4885KDM4E 1921/4885MEN1 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.