Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432749 | 0.94 | ITGB1 (0.66) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| SCHEMBL2430235 | 0.88 | ITGB1 (0.58) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| SCHEMBL6764792 | 0.88 | ITGB1 (0.58) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| SCHEMBL2429874 | 0.84 | ITGB1 (0.65) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| SCHEMBL1237542 | 0.84 | ITGB1 (0.41) | ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL2437226 | 0.82 | ITGB1 (0.64) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| SCHEMBL2430016 | 0.82 | ITGB1 (0.51) | ITGB1ITGA4KDM1A | |
| SCHEMBL2433300 | 0.81 | ITGB1 (0.71) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| SCHEMBL1170751 | 0.81 | ITGB1 (0.70) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| Water SCHEMBL2128631 | 0.81 | ITGB1 (0.69) | ITGB1ITGA4KDM1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110945-A1 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110945-A1 | Vla-4 inhibitors | VCAM1, ITGA1, ITGB4 | ITGB1 5/4885ITGA4 4/4885KDM1A 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.