SCHEMBL67673

SCHEMBL67673

Cc1cc(O)c(Sc2cc(Cl)c(C)cc2O)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
ALOX15 P16050 7/20 0.45
ALDH1A1 P00352 7/20 0.45
CYP3A4 P08684 7/20 0.45
HPGD P15428 7/20 0.45
HSD17B10 Q99714 7/20 0.45
MAPT P10636 6/20 0.45
HIF1A Q16665 4/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
ALOX12 P18054 4/20 0.45
GAA P10253 3/20 0.45
TP53 P04637 3/20 0.45
HTT P42858 3/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
HSP90AA1 P07900 2/20 0.45
PLA2G1B P04054 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19198121 0.96 LMNA (0.47) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL26773039 0.84 LMNA (0.48) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL17378588 0.80 HSD17B10 (0.58) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL68646 0.80 ALOX15 (0.52) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL14283830 0.78 ALOX15 (0.52) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL11673783 0.78 HSD17B10 (0.50) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL2662863 0.78 LMNA (0.60) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL4062679 0.75 LMNA (0.58) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL4853924 0.75 HSD17B10 (0.60) LMNAALOX15ALDH1A1CYP3A4HPGD
SCHEMBL17498327 0.73 ALOX15 (0.45) LMNAALOX15ALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 LMNA 2207/4885ALOX15 1966/4885ALDH1A1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.