SCHEMBL68646

SCHEMBL68646

Cc1cc(O)c(Sc2cc(C)c(C)cc2O)cc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.52
MAPT P10636 6/20 0.52
HPGD P15428 5/20 0.52
HSD17B10 Q99714 5/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
TP53 P04637 4/20 0.52
LMNA P02545 4/20 0.52
ALOX12 P18054 3/20 0.52
GAA P10253 3/20 0.52
ALDH1A1 P00352 7/20 0.50
CYP3A4 P08684 3/20 0.50
HIF1A Q16665 3/20 0.50
MAPK1 P28482 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TSHR P16473 1/20 0.50
KDM4E B2RXH2 4/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14283830 0.86 ALOX15 (0.52) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL29599384 0.81 ALOX15 (0.59) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL2479249 0.81 ALOX15 (0.59) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL17498327 0.80 ALOX15 (0.45) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL67673 0.80 LMNA (0.50) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL19198121 0.77 LMNA (0.47) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL17498321 0.75 CYP3A4 (0.44) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL30385731 0.75 MAPT (0.56) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL69809 0.75 MAPT (0.56) ALOX15MAPTHPGDHSD17B10MEN1
SCHEMBL5153024 0.73 ALOX15 (0.46) ALOX15MAPTHPGDHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0457334-B1 Carbonates of acetylenic alcohols NIPPON PAINT CO LTD (JP) 1994-08-10 EP disclosed
US-5258542-A Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1993-11-02 US disclosed
US-5194653-A Useful in making heat resistant liquid crystalline polymers NIPPON PAINT COMPANY, LIMITED (JP) 1993-03-16 US disclosed
EP-0457334-A1 Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1991-11-21 EP disclosed
US-4287366-A BY OXIDATION OF THE CORRESPONDING SULFIDE OR SULFOXIDE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF AN ALKALI METAL HYDROXIDE MITSUI TOATSU CHEMICALS, INC. (JP) 1981-09-01 US disclosed
US-4275240-A OXIDATION OF 2,2'-BISPHENOL SULFIDES IN A SOLVENT MITSUI TOATSU CHEMICALS, INC. (JP) 1981-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALOX15 1966/4885MAPT 1923/4885HPGD 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.