Sugi Predict

Sugi Predict / Compounds / SCHEMBL6767360

SCHEMBL6767360

SCHEMBL6767360

Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(-c4cccs4)c3c2)c1=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.33
▸ MEN1 O00255 6/20 0.33
▸ KMT2A Q03164 6/20 0.33
▸ USP2 O75604 5/20 0.33
▸ CYP1A2 P05177 5/20 0.33
▸ CASP1 P29466 5/20 0.33
▸ CASP7 P55210 5/20 0.33
▸ GAA P10253 4/20 0.33
▸ HIF1A Q16665 4/20 0.33
▸ CYP3A4 P08684 4/20 0.33
▸ HSD17B10 Q99714 4/20 0.33
▸ GLA P06280 3/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ CLK4 Q9HAZ1 2/20 0.33
▸ PTGS2 P35354 2/20 0.33
▸ KDM4E B2RXH2 6/20 0.33
▸ HPGD P15428 6/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ LMNA P02545 2/20 0.33
▸ L3MBTL1 Q9Y468 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6773262 0.85 PTGS2 (0.32) PTGS2
SCHEMBL7462316 0.85 ALDH1A1 (0.33) ALDH1A1MEN1KMT2AGAAKDM4E
SCHEMBL6772344 0.84 — —
SCHEMBL6772693 0.84 MAPT (0.32) MAPT
SCHEMBL6766199 0.84 TRPV1 (0.30) —
SCHEMBL6771155 0.83 ADORA1 (0.31) ADORA1
SCHEMBL6766878 0.83 PTGS2 (0.35) PTGS2
SCHEMBL6771354 0.83 TP53 (0.32) —
SCHEMBL6770297 0.82 TRPV1 (0.39) PTGS2
SCHEMBL6777585 0.82 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706663-B2 CHEMICAL INTERMEDIATES WYETH 2004-03-16 — — US claimed
EP-1274708-A1 HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2003-01-15 — — EP claimed
US-20020028748-A1 Herbicidal 3 -heterocyclic substituted benzisothiazole and benzisoxazole compounds INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-03-07 — — US claimed
WO-2001079203-A1 HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-10-25 — — WO claimed
US-6706663-B2 CHEMICAL INTERMEDIATES WYETH 2004-03-16 — — US disclosed
EP-1274708-A1 HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2003-01-15 — — EP disclosed
US-20020028748-A1 Herbicidal 3 -heterocyclic substituted benzisothiazole and benzisoxazole compounds INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-03-07 — — US disclosed
WO-2001079203-A1 HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-10-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028748-A1 Herbicidal 3 -heterocyclic substituted benzisothiazole and benzisoxazole compounds CYP4X1, HAX1, DDT ALDH1A1 201/4885MEN1 3770/4885KMT2A 926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.