Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767362 | 0.85 | PDE3B (0.65) | SMN1; SMN2GAAPKMPDE3BPDE3A | |
| SCHEMBL6768474 | 0.84 | GAA (0.51) | SMN1; SMN2GAAPKMPDE3BPDE3A | |
| SCHEMBL6763587 | 0.80 | GAA (0.53) | SMN1; SMN2GAAPKMMAPTALDH1A1 | |
| SCHEMBL6772737 | 0.79 | GAA (0.56) | SMN1; SMN2GAAPKMMAPTALDH1A1 | |
| SCHEMBL27987840 | 0.78 | CA12 (0.50) | SMN1; SMN2PKMPDE3BPDE3AP2RY12 | |
| SCHEMBL6773336 | 0.78 | TSHR (0.58) | SMN1; SMN2GAAPKMPDE3BPDE3A | |
| SCHEMBL6768025 | 0.78 | PARP1 (0.58) | SMN1; SMN2GAAPKMPDE3BPDE3A | |
| SCHEMBL14816222 | 0.78 | PDE3B (0.64) | GAAPDE3BPDE3AP2RY12MAPT | |
| SCHEMBL16729160 | 0.78 | ALOX15 (0.52) | SMN1; SMN2PKMMAPTALDH1A1MEN1 | |
| SCHEMBL5654906 | 0.77 | NOS1 (0.51) | SMN1; SMN2PKMPDE3BPDE3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |