Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.53 |
| ▸ | RARB | P10826 | 2/20 | 0.53 |
| ▸ | RARG | P13631 | 2/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 4/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771144 | 0.82 | RARA (0.52) | RARARARBRARGPTGDR2MAPT | |
| SCHEMBL6771150 | 0.82 | RARA (0.52) | RARARARBRARGPTGDR2MAPT | |
| SCHEMBL6765901 | 0.80 | CYP1B1 (0.44) | RARARARBRARGPTGDR2MAPT | |
| SCHEMBL6765906 | 0.80 | CYP1B1 (0.44) | RARARARBRARGPTGDR2MAPT | |
| SCHEMBL6770006 | 0.76 | HDAC1 (0.56) | RARARARBRARGMAPTHDAC1 | |
| SCHEMBL6767431 | 0.74 | PTGDR2 (0.48) | PTGDR2MAPTHDAC1HDAC6HDAC3 | |
| SCHEMBL6227625 | 0.70 | RARA (0.55) | RARARARBRARGHDAC1HDAC6 | |
| SCHEMBL1764037 | 0.68 | HDAC1 (0.47) | RARARARBRARGPTGDR2MAPT | |
| SCHEMBL8122127 | 0.68 | RARA (0.64) | RARARARBRARGHDAC1HDAC6 | |
| SCHEMBL8119608 | 0.68 | RARA (0.68) | RARARARBRARGHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683092-B1 | BREAST AND/OR PROSTATE CANCER | ALLERGAN, INC. | 2004-01-27 | — | — | US | disclosed |