Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771147 | 0.82 | HDAC1 (0.43) | PTGDR2HDAC1HDAC6PARK7TP53 | |
| SCHEMBL1764037 | 0.81 | HDAC1 (0.47) | PTGDR2HDAC1HDAC6TP53MAPT | |
| SCHEMBL6765905 | 0.81 | TP53 (0.45) | PTGDR2HDAC1HDAC6TP53MAPT | |
| SCHEMBL1764561 | 0.81 | HDAC1 (0.48) | PTGDR2HDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL6769021 | 0.81 | HDAC1 (0.46) | HDAC1HDAC6TP53MAPTALDH1A1 | |
| SCHEMBL6769139 | 0.81 | HDAC1 (0.46) | HDAC1HDAC6TP53MAPTALDH1A1 | |
| SCHEMBL6765782 | 0.81 | HDAC1 (0.46) | HDAC1HDAC6TP53MAPTALDH1A1 | |
| SCHEMBL4427655 | 0.81 | HDAC1 (0.46) | HDAC1HDAC6TP53MAPTALDH1A1 | |
| SCHEMBL6770006 | 0.78 | HDAC1 (0.56) | HDAC1HDAC6TP53MAPTHPGD | |
| SCHEMBL6767428 | 0.74 | RARA (0.53) | PTGDR2HDAC1HDAC6MAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683092-B1 | BREAST AND/OR PROSTATE CANCER | ALLERGAN, INC. | 2004-01-27 | — | — | US | disclosed |