Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.52 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | RARG | P13631 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771144 | 1.00 | RARA (0.52) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL6765901 | 0.93 | CYP1B1 (0.44) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL6765906 | 0.93 | CYP1B1 (0.44) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL6770057 | 0.82 | HDAC3 (0.48) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL6770058 | 0.82 | HDAC3 (0.48) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL13827617 | 0.82 | RARB (0.51) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL6767428 | 0.82 | RARA (0.53) | RARARARBRARGMAPTKMT2A | |
| SCHEMBL6771147 | 0.79 | HDAC1 (0.43) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL6765664 | 0.75 | RARB (0.45) | RARARARBRARGPTPN1PTPN12 | |
| SCHEMBL6765666 | 0.75 | RARB (0.45) | RARARARBRARGPTPN1PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683092-B1 | BREAST AND/OR PROSTATE CANCER | ALLERGAN, INC. | 2004-01-27 | — | — | US | disclosed |