SCHEMBL6767463

SCHEMBL6767463

CCS[C@@H]1O[C@H](COCc2ccccc2)[C@H](O)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 6/20 0.49
TACR2 P21452 2/20 0.45
SSTR1 P30872 2/20 0.43
SSTR2 P30874 2/20 0.43
SSTR3 P32745 2/20 0.43
SSTR5 P35346 2/20 0.43
GJB2 P29033 1/20 0.41
SLC6A2 P23975 2/20 0.40
HTR1A P08908 1/20 0.40
NT5E P21589 1/20 0.39
HSPA5 P11021 1/20 0.39
PDE4D Q08499 1/20 0.38
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19276600 1.00 SSTR4 (0.49) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL19276601 1.00 SSTR4 (0.49) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL6952281 0.94 SSTR4 (0.47) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL17822287 0.91 SSTR4 (0.61) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL13402617 0.91 SSTR4 (0.47) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL19272030 0.91 SSTR4 (0.45) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL1521205 0.89 SSTR1 (0.47) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL1521538 0.89 SSTR1 (0.47) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL12083220 0.89 SSTR1 (0.47) SSTR4TACR2SSTR1SSTR2SSTR3
SCHEMBL6892339 0.89 SSTR1 (0.47) SSTR4TACR2SSTR1SSTR2SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3197907-B1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 MAX PLANCK GESELLSCHAFT (DE) 2019-09-04 EP disclosed
US-10220083-B2 Vaccines against Streptococcus pneumoniae serotype 8 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2019-03-05 US disclosed
US-20170239341-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-08-24 US disclosed
EP-3197907-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 Max-Planck-Gesellschaft zur Förderung der Wissenschaften (DE) 2017-08-02 EP disclosed
WO-2016046420-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-03-31 WO disclosed
EP-3000820-A1 Synthetic vaccines against Streptococcus pneumoniae serotype 8 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-03-30 EP disclosed
US-6723843-B2 USE OF A 2-SUBSTITUTED-1,3-DIOXOCYCLOALKYL LINKER GROUP TO COUPLE SACCHARIDE GROUPS OF BOTH THE O-GLYCOSIDE AND N-GLYCOSIDE TYPE TO A POLYMER SUPPORT IN A SOLID PHASE SYSTHESIS PROCESS ALCHEMIA PTY LTD (AU) 2004-04-20 US disclosed
US-6573337-B1 Dioxocyclohexane compound linker for solid-phase synthesis of oligosaccharides ALCHEMIA PTY LTD (AU) 2003-06-03 US disclosed
US-20030027925-A1 Oligosaccharide synthesis ALCHEMIA PTY LTD 2003-02-06 US disclosed
EP-0923528-B1 OLIGOSACCHARIDE SYNTHESIS ALCHEMIA PTY LTD (AU) 2002-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10220083-B2 Vaccines against Streptococcus pneumoniae serotype 8 LGALS8, SIGLEC7, FUT5 SSTR4 2332/4885TACR2 3961/4885SSTR1 2106/4885
US-20170239341-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 LGALS8, SIGLEC7, FUT5 SSTR4 2332/4885TACR2 3961/4885SSTR1 2106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.