Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767630 | 0.98 | MMP1 (0.45) | MMP1MMP9MMP13MMP2ALDH1A1 | |
| SCHEMBL6773578 | 0.97 | MMP1 (0.44) | MMP1MMP9MMP13MMP2ALDH1A1 | |
| SCHEMBL6770871 | 0.97 | MMP1 (0.44) | MMP1MMP9MMP13MMP2ALDH1A1 | |
| SCHEMBL6770618 | 0.88 | ALDH1A1 (0.45) | MMP13ALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL6772123 | 0.86 | KDM4E (0.45) | ALDH1A1KDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL6778063 | 0.85 | KDM4E (0.44) | ALDH1A1KDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL6767549 | 0.84 | MAPT (0.45) | ALDH1A1KDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL6767876 | 0.80 | ALDH1A1 (0.49) | MMP1MMP9MMP13MMP2ALDH1A1 | |
| SCHEMBL6577251 | 0.76 | MMP13 (0.52) | MMP1MMP9MMP13MMP2ALDH1A1 | |
| SCHEMBL6579753 | 0.76 | MMP13 (0.52) | MMP1MMP9MMP13MMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210326-B1 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1210326-A2 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-06-05 | — | — | EP | claimed |
| WO-2001012592-A2 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-02-22 | — | — | WO | claimed |
| EP-1210326-B1 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6677355-B1 | DIBENZOFURAN-3-(SULFONYLAMINO OR SULFINAMINO) DERIVATIVES; MULTIPLE SCLEROSIS, ATHEROSCLEROSIS, HEART FAILURE, PERIODONTAL DISEASE, OSTEOARTHRITIS, AUTOIMMUNE DISEASE; ANTICARCINOGENIC AGENTS | WARNER-LAMBERT COMPANY | 2004-01-13 | — | — | US | disclosed |