Luteolinidin

Luteolinidin

SCHEMBL676807

Oc1cc(O)c2ccc(-c3ccc(O)c(O)c3)[o+]c2c1.[Cl-]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Luteolinidin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CD38 P28907 11/20 0.97
GLO1 Q04760 5/20 0.63
SNCA P37840 3/20 0.63
DPP4 P27487 3/20 0.63
F2 P00734 1/20 0.60
NR1H2 P55055 1/20 0.60
NR1H3 Q13133 1/20 0.60
OR51E2 Q9H255 2/20 0.50
EGFR P00533 2/20 0.46
KDR P35968 2/20 0.46
EP300 Q09472 2/20 0.46
CREBBP Q92793 2/20 0.46
APP P05067 2/20 0.41
ALOX5 P09917 1/20 0.40
MAOA P21397 1/20 0.38
QDPR P09417 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Luteolinidin SCHEMBL30159678 0.98 CD38 (1.00) CD38GLO1SNCADPP4F2
Luteolinidin SCHEMBL676808 0.98 CD38 (1.00) CD38GLO1SNCADPP4F2
SCHEMBL7045086 0.87 CD38 (0.79) CD38GLO1SNCADPP4F2
Hydrochloric Acid SCHEMBL29413086 0.87 CD38 (0.73) CD38GLO1SNCADPP4F2
Hydrochloric Acid SCHEMBL29392598 0.87 CD38 (0.73) CD38GLO1SNCADPP4F2
Hydrochloric Acid SCHEMBL1366891 0.87 CD38 (0.73) CD38GLO1SNCADPP4F2
Hydrochloric Acid SCHEMBL6131747 0.85 CD38 (0.71) CD38GLO1SNCADPP4F2
Hydrochloric Acid SCHEMBL11317960 0.85 CD38 (0.71) CD38GLO1SNCADPP4F2
SCHEMBL5692415 0.85 CD38 (0.76) CD38GLO1SNCADPP4F2
SCHEMBL6131745 0.83 CD38 (0.73) CD38GLO1SNCADPP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 942 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260090969-A1 COMPOSITIONS THAT PROTECT CELLS FROM OXIDATIVE AND MITOCHONDRIAL STRESS Nuchido Limited (GB) 2026-04-02 US claimed
EP-4622686-A1 SPRAY PATCH COMPOSITION, PROCESS FOR PREPARING IT AND KIT Fondazione Istituto Italiano di Tecnologia (IT) 2025-10-01 EP claimed
WO-2025093707-A1 METHOD FOR SUPPRESSING CAR-T CELLS UNRESPONSIVENESS FOR IMPROVING CANCER IMMUNOTHERAPY Université de Lausanne (CH) 2025-05-08 WO claimed
US-20250064094-A1 COMPOSITIONS FOR FOOD COLORING AND ANTIOXIDANT SUPPLEMENTATION DERIVED FROM SORGHUM RedLeaf Biologics, Inc. (US) 2025-02-27 US claimed
EP-4472625-A1 COMPOSITIONS FOR FOOD COLORING AND ANTIOXIDANT SUPPLEMENTATION DERIVED FROM SORGHUM Redleaf Biologics, Inc. (US) 2024-12-11 EP claimed
WO-2024248183-A1 HAIR-PROTECTING COMPOSITION AND HAIR CARE PRODUCT COMPRISING SAME 주식회사 모다바이오 2024-12-05 WO claimed
EP-4426338-A2 CD38 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY Intellia Therapeutics, Inc. (US) 2024-09-11 EP claimed
WO-2024110911-A1 SPRAY PATCH COMPOSITION, PROCESS FOR PREPARING IT AND KIT FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2024-05-30 WO claimed
US-20230355769-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS Natural Extraction Systems, LLC (US) 2023-11-09 US claimed
US-20230338331-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS Natural Extraction Systems, LLC (US) 2023-10-26 US claimed
EP-1172090-B1 Skin dyeing compositions comprising dihydroxyacetone and a flavylium salt non substituted in position 3 OREAL (FR) 2005-03-09 EP claimed
EP-1172093-B1 Compositions for coloring the skin containing flavylium salt compounds unsubstituted in position 3 and an organomodified silicone OREAL (FR) 2004-12-01 EP claimed
WO-2004100685-A1 MOLD INHIBITOR INTEGRATED WITHIN A MATRIX AND METHOD OF MAKING SAME MARKHAM JOSEPH P (US) 2004-11-25 WO claimed
US-20040223999-A1 Mold inhibitor integrated within a matrix and method of making same MARKHAM JOSEPH P (US) 2004-11-11 US claimed
EP-1172092-B1 Compositions for coloring the skin containing at least one UV filter and flavylium salt compounds unsubstituted in position 3 OREAL (FR) 2004-09-15 EP claimed
WO-2002024212-A1 CHOLESTEROL IN BLOOD-LOWERING COMPOSITION AND ITS COMPLEX, AND METHOD FOR PREPARING THEM ULTIMATE LIFE TECHNOLOGY CO., LTD. (KR) 2002-03-28 WO claimed
WO-1997041137-A1 USE OF ANTHOCYANIDIN AND ANTHOCYANIDIN DERIVATIVES UNIFOB (NO) 1997-11-06 WO claimed
EP-0785790-A1 USE OF ANTHOCYANIDIN AND DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS UNIFOB STIFTELSEN UNIVERSITETSFORSKNING BERGEN (NO) 1997-07-30 EP claimed
WO-1996011692-A9 USE OF ANTHOCYANIDIN AND DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS 1996-06-20 WO claimed
WO-1996011692-A1 USE OF ANTHOCYANIDIN AND DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS UNIFOB STIFTELSEN UNIVERSITETSFORSKNING BERGEN (NO) 1996-04-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090969-A1 COMPOSITIONS THAT PROTECT CELLS FROM OXIDATIVE AND MITOCHONDRIAL STRESS NLN, TFAM, CYP27B1 CD38 974/4885GLO1 2231/4885SNCA 1789/4885
US-20230355769-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS CNR2, CNR1, UGT8 CD38 2308/4885GLO1 2357/4885SNCA 958/4885
US-20230338331-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS CNR2, CNR1, UGT8 CD38 2308/4885GLO1 2357/4885SNCA 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.