Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773648 | 0.87 | TLR7 (0.48) | ALDH1A1TLR7TLR8MEN1MAPT | |
| SCHEMBL6779320 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRTLR7TLR8BRD4 | |
| SCHEMBL6774073 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRTLR7TLR8BRD4 | |
| SCHEMBL6768441 | 0.82 | TLR7 (0.47) | TLR7TLR8KDM4EHSD17B10 | |
| SCHEMBL6773147 | 0.82 | TLR7 (0.45) | TLR7TLR8 | |
| SCHEMBL6771916 | 0.82 | TLR7 (0.48) | TLR7TLR8KDM4EHPGDLMNA | |
| SCHEMBL6775141 | 0.81 | TLR7 (0.51) | TLR7TLR8MAPT | |
| SCHEMBL6778162 | 0.81 | TLR7 (0.41) | ALDH1A1TSHRTLR7TLR8CYP3A4 | |
| SCHEMBL6777954 | 0.81 | TLR7 (0.41) | ALDH1A1TLR7TLR8KDM4EHPGD | |
| SCHEMBL6285998 | 0.80 | TLR7 (0.40) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |